Protein Info for A4249_RS13155 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: heparinase II/III family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 615 PF07940: Hepar_II_III" amino acids 359 to 604 (246 residues), 134.1 bits, see alignment E=3e-43

Best Hits

KEGG orthology group: None (inferred from 74% identity to bsb:Bresu_0283)

Predicted SEED Role

"Heparinase II/III-like"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A160I0W0 at UniProt or InterPro

Protein Sequence (615 amino acids)

>A4249_RS13155 heparinase II/III family protein (Brevundimonas sp. GW460-12-10-14-LB2)
MSPLGPFAPRGPETTLDVASGQIPGLPGAPVRTPVRSGDAAAGPGLWPAIAGRMATRQLW
IELYGLPGYGLTLGSPLGGGKVTAFAATPRDFRPHDPAPGRNVLAGRFMLAGASMEVEPP
TDPWNRPSPSRPFAVELHAFAWLPGLMAQGDRGAREALRLTLAWADAFARWSPFAWGPEI
LARRVVNLACGARRMGAVATEAERLKLADSLARQTRQLLRPPGGLASRAERLTAAAIGGC
VLAGAPGQALRRRALSRLDGALKTTVQADGGHASRSPEAGLELLLDLLTLDDALSQLSEP
TPESISAAIARLTQGLRLLTLPDGRLASFQGGGPSTFERVAAACAHDDEAMASGDVAPAA
TGTVAGLTRIASPLLTIIADTAPPARDAWGAAACAQPLALEIACGKDRLVTGSGWTPAST
DRQALRLTPAHSTLTLGERSLNEPLGGWKGELLGPRLVGPPIHVTTDLRDGDGAVWLEME
HDGWNELFGLNHQRRLYLDQRLDELRAEEKLFPTPGRKEMVRQIAAPYAIRFHLEPGVQA
SLARDRRSILLRGASGRGWWFRTDGPDVAIEPSVHIDAGLTRRSLQIVVRGSARTDSETK
IRWKLSPAGASGEPT