Protein Info for A4249_RS11980 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: amidohydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 433 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details TIGR01891: amidohydrolase" amino acids 40 to 418 (379 residues), 312 bits, see alignment E=2.9e-97 PF01546: Peptidase_M20" amino acids 97 to 426 (330 residues), 120.3 bits, see alignment E=1.1e-38 PF07687: M20_dimer" amino acids 225 to 322 (98 residues), 37.7 bits, see alignment E=1.7e-13

Best Hits

KEGG orthology group: None (inferred from 78% identity to bsb:Bresu_0631)

Predicted SEED Role

"N-acetyl-L,L-diaminopimelate deacetylase (EC 3.5.1.47)" in subsystem Lysine Biosynthesis DAP Pathway (EC 3.5.1.47)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.1.47

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A160I0X9 at UniProt or InterPro

Protein Sequence (433 amino acids)

>A4249_RS11980 amidohydrolase (Brevundimonas sp. GW460-12-10-14-LB2)
MRRLFAASTMALLLAAGAAQAQVDTASVDAAVQRVMPEVVAWRRDFHQHPELGFAETRSA
GVIAEHLRSLGLEVRPGVGKTGVIGVLRGARPGRTVALRADMDALPVQEATGLDFASSAT
GTYMGNTVPVAHACGHDMHMAMLMGAAEVLAGMKDRIAGTVVFVFQPAEEGAPPGEPKGG
AALMIAEGALNDPKPEAIFGLHVVPGRPGSVFYRPEGFMAASDRVDIRLKGKQTHGAWPW
RGVDVIAVAGQVVETVNTLTARTVDPTTTPTVFTIATINAGVRYNIIPNSATLSGTLRTF
DTAQRDALVARAETAIDHVAEAYGATAEFGVKQNAALVFNDPDLSAWLAPVLTEAAGEGN
VNPATPPTTVAEDFSYFQQVIPGVFYHLGASPDGVDPATSAPNHSPEFSPNENVLPLGVK
THVLTVLRFLERS