Protein Info for A4249_RS11955 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: 2'-deoxycytidine 5'-triphosphate deaminase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF06559: DCD
  • amino acids 9 to 173 (165 residues), 241.6 bits, E=5.8e-76
  • amino acids 180 to 339 (160 residues), 248.9 bits, E=3.5e-78

Best Hits

KEGG orthology group: K01494, dCTP deaminase [EC: 3.5.4.13] (inferred from 87% identity to bsb:Bresu_0626)

Predicted SEED Role

"Deoxycytidine triphosphate deaminase (EC 3.5.4.13)" (EC 3.5.4.13)

MetaCyc Pathways

• superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli) (12/14 steps found)
• pyrimidine deoxyribonucleotides de novo biosynthesis II (5/7 steps found)

KEGG Metabolic Maps

• Pyrimidine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.4.13

Sequence Analysis Tools

See A0A160I1J8 at UniProt or InterPro

Protein Sequence (341 amino acids)

>A4249_RS11955 2'-deoxycytidine 5'-triphosphate deaminase (Brevundimonas sp. GW460-12-10-14-LB2)
MSSFQAPRPGILPAQSIETLIAAGAVTSDTPFDHDQVQPASLDLRLSDQAWRVRASFLPG
RRKVEDRIADVAMHAIEITEAGVVLEKGCVYIVRLQERLKLPQGLIARANPKSSTGRVDV
FVRLLTDQGASFDDVAEGYDGPLYMEVAPQTFSILVRPGTRLNQLRLKAGDPPKLETRSV
GVDLQGGDIVGFRGRRHAGVVDLDHIDGHDPRDFWEPLSLRRGELLLDPGEFYILASSDD
VEIPVDQAAEMTPIDPSVGEFRVHYAGFFDPGFGTDEAHGAGSKGVLEVRTHDTPFLLEH
GQIVARLVYEPLTERPSRLYGESGSHYQNQGLKLSKHFKAW