Protein Info for A4249_RS11770 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: cation transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 222 transmembrane" amino acids 33 to 54 (22 residues), see Phobius details amino acids 60 to 81 (22 residues), see Phobius details amino acids 92 to 112 (21 residues), see Phobius details amino acids 124 to 144 (21 residues), see Phobius details amino acids 164 to 181 (18 residues), see Phobius details amino acids 187 to 206 (20 residues), see Phobius details PF01545: Cation_efflux" amino acids 35 to 208 (174 residues), 51.1 bits, see alignment E=7.7e-18

Best Hits

KEGG orthology group: None (inferred from 79% identity to bsb:Bresu_1649)

Predicted SEED Role

"Cobalt-zinc-cadmium resistance protein CzcD" in subsystem Cobalt-zinc-cadmium resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A160I0X3 at UniProt or InterPro

Protein Sequence (222 amino acids)

>A4249_RS11770 cation transporter (Brevundimonas sp. GW460-12-10-14-LB2)
MTTPAPTESCAPARGCCGHQVRFDGASPAYRRVLMAVIALNLGGFFAVAAGGLMQGSAAL
AANAMDFLADSATYAVSLWAIGKSVRVRSGAAVFKSASLLVMAVSILGYAVWRAVTGQPP
EGVVITGLGLVGFAANLIAALLLVRFRDGDANVRSVWLCTRNDLIHSLGVAAAGGLVWLT
GSRWPDLLAGLLLGGVFLQSAISILVQARAESRAAHAAVRTL