Protein Info for A4249_RS11380 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: FKBP-type peptidyl-prolyl cis-trans isomerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 171 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF01346: FKBP_N" amino acids 29 to 58 (30 residues), 37 bits, see alignment 5.1e-13 PF00254: FKBP_C" amino acids 68 to 154 (87 residues), 92.8 bits, see alignment E=1.4e-30

Best Hits

KEGG orthology group: K03773, FKBP-type peptidyl-prolyl cis-trans isomerase FklB [EC: 5.2.1.8] (inferred from 59% identity to bsb:Bresu_0947)

Predicted SEED Role

No annotation

Isozymes

Compare fitness of predicted isozymes for: 5.2.1.8

Use Curated BLAST to search for 5.2.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A168NN61 at UniProt or InterPro

Protein Sequence (171 amino acids)

>A4249_RS11380 FKBP-type peptidyl-prolyl cis-trans isomerase (Brevundimonas sp. GW460-12-10-14-LB2)
MNFGWGRAAIVAAFLLSGCGQAEPVDPNAGKAEAAAFMAQNAKEEGVQTLPSGLQYKVVQ
AGPAGGVSPDRNDLVKVDYEGKLVDNSVFDSSFARGAPAVFTPEEVVKGWTEALQKMRVG
DEWLLYVPPELGYGEQGNPKIPANSVLIFRLKLLDVAKVPGGGSGVGTAMG