Protein Info for A4249_RS11075 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: phenylalanine--tRNA ligase subunit beta

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 807 TIGR00472: phenylalanine--tRNA ligase, beta subunit" amino acids 1 to 806 (806 residues), 640.1 bits, see alignment E=2.8e-196 PF01588: tRNA_bind" amino acids 46 to 145 (100 residues), 70.6 bits, see alignment E=2.4e-23 PF03483: B3_4" amino acids 212 to 392 (181 residues), 195.4 bits, see alignment E=1.5e-61 PF03484: B5" amino acids 412 to 480 (69 residues), 65.1 bits, see alignment E=1.4e-21 PF17759: tRNA_synthFbeta" amino acids 493 to 693 (201 residues), 147.9 bits, see alignment E=7.4e-47 PF03147: FDX-ACB" amino acids 719 to 806 (88 residues), 76.8 bits, see alignment E=3.5e-25

Best Hits

KEGG orthology group: K01890, phenylalanyl-tRNA synthetase beta chain [EC: 6.1.1.20] (inferred from 82% identity to bsb:Bresu_0491)

Predicted SEED Role

"Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20)" (EC 6.1.1.20)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 6.1.1.20

Use Curated BLAST to search for 6.1.1.20

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A160I189 at UniProt or InterPro

Protein Sequence (807 amino acids)

>A4249_RS11075 phenylalanine--tRNA ligase subunit beta (Brevundimonas sp. GW460-12-10-14-LB2)
MKFTLSWLKDHLETEADVHQIAEAMTMAGLEVEEVLDPAAKLAPFTVAKIVSAERHPNAD
RLQVCQVETVDGMKEIVCGAPNARAGLTTIYAPIGAYVPGLGVTLVEKPVRGVVSNGMLC
SASELELSDESDGIQELPPEIPVGTPVAGLFGAEPVIDFEVTPNRPDWLGVAGIARDLAA
ASVGKLKHFDIAVVRGAFPSPISVRLESPEMCPVFAGRVIRGVKNGPSPAWLQKRLTAIG
LRSINRLVDVTNLIAYDRARPLHVYDVAKLSGTEIVVRAGQVSAATGEHEHLIALDGKTY
AASAAECVIADAGGERPIGLGGVMGGESTGCDETTTDVFLESAWFDPLVIAQTGRSLGIH
SDAQYRFARGVDPVSVTPGLELATRLILDLCGGEPSEIVFVGEPPASPAPFAFDPAYVKR
LSGMDLADDRIGTILGQLGFLVQAAPAGQAEAWLVTPPSWRRDVEGPADLVEEVARIEGF
DSLPDTPLPEVARPAGGVLSPRQARVRTARRALAALGYAEAVTWSFTKQSTAALFGGGDD
RLVLENPIAADLDCMRPSALPNLVQAAARNAARGFADAALFEIGPIYLGDGPADQRTVIA
GLVAPHAARHWAGAGEDALFTLKGDLTTLLEEIGAPVASLQLVQGQNRDWWHPGRSARLQ
LGPKNVMVEFGELHPRVLKALDADGPMLGFEIVLDNVPEPRGKSGKARGTADLSALMPLT
RDFAFVVEDAKPVGDLVRAATGADKALIADVHVFDVYRGKGVDEGFKSVALEVMIQPREA
TLTEAEIEALTAKVVGAVEKQGGKLRA