Protein Info for A4249_RS10270 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: histidine kinase dimerization/phosphoacceptor domain -containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 431 PF13185: GAF_2" amino acids 79 to 220 (142 residues), 47 bits, see alignment E=9.6e-16 PF01590: GAF" amino acids 82 to 220 (139 residues), 43.2 bits, see alignment E=1.7e-14 PF07536: HWE_HK" amino acids 242 to 306 (65 residues), 41.4 bits, see alignment E=6.1e-14 PF07568: HisKA_2" amino acids 242 to 313 (72 residues), 73.8 bits, see alignment E=2.9e-24 PF13581: HATPase_c_2" amino acids 319 to 407 (89 residues), 45.2 bits, see alignment E=2.8e-15 PF02518: HATPase_c" amino acids 337 to 430 (94 residues), 42.7 bits, see alignment E=2.1e-14

Best Hits

KEGG orthology group: None (inferred from 74% identity to bsb:Bresu_1206)

Predicted SEED Role

"signal transduction histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A168NY90 at UniProt or InterPro

Protein Sequence (431 amino acids)

>A4249_RS10270 histidine kinase dimerization/phosphoacceptor domain -containing protein (Brevundimonas sp. GW460-12-10-14-LB2)
MPHTRPPSDPGLTPEIAELVAEVWADTASQTQIQMDDPVAPKVEDAPTPETRSIADELRY
RLKQQSLLARFGEVALRERDRQALLDAACVVCADGLETPLSKVLIHNESRDRLVLVAGVG
WSGEVEGHASLGVELDSPAGYAFQTGKPLISNHLENEQRFHTPKLLADHGVRRAINVLIR
PELDGEPWGVLEVDSPDEGQFDARDALFLDAFAAVVGAAIARQQTEQRLLAAIEHQALLT
REVSHRVKNSLSLVSSLLSMQARGAASDEVRAALATAGSRIQAISEVHDQLWRGADVQTV
ILSDFLCQLCEAIDAGSDRHVVTCEASDAPLGADIAIPLGLIVNELVTNAIKYAYGPEGG
GVSVTGRIADGRLTVTVADQGKGFDLIAARSDRSLGMRVINNLVRQIGGTIENRSPGSGQ
GATLVVEAPAT