Protein Info for A4249_RS09990 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: ammonium transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 426 transmembrane" amino acids 31 to 52 (22 residues), see Phobius details amino acids 61 to 85 (25 residues), see Phobius details amino acids 125 to 147 (23 residues), see Phobius details amino acids 154 to 176 (23 residues), see Phobius details amino acids 188 to 210 (23 residues), see Phobius details amino acids 222 to 242 (21 residues), see Phobius details amino acids 253 to 272 (20 residues), see Phobius details amino acids 284 to 305 (22 residues), see Phobius details amino acids 311 to 329 (19 residues), see Phobius details amino acids 341 to 364 (24 residues), see Phobius details amino acids 377 to 398 (22 residues), see Phobius details TIGR00836: ammonium transporter" amino acids 30 to 422 (393 residues), 419 bits, see alignment E=1e-129 PF00909: Ammonium_transp" amino acids 31 to 422 (392 residues), 382.8 bits, see alignment E=8.3e-119

Best Hits

Swiss-Prot: 51% identical to Y663_METTH: Putative ammonium transporter MTH_663 (MTH_663) from Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)

KEGG orthology group: K03320, ammonium transporter, Amt family (inferred from 77% identity to bsb:Bresu_3085)

MetaCyc: 45% identical to ammonium transporter (Escherichia coli K-12 substr. MG1655)
RXN-9615

Predicted SEED Role

"Ammonium transporter" in subsystem Ammonia assimilation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A160I061 at UniProt or InterPro

Protein Sequence (426 amino acids)

>A4249_RS09990 ammonium transporter (Brevundimonas sp. GW460-12-10-14-LB2)
MAAGAANAQDAAAALLGHQAALELDSAGASWLGTSTALVLLMTLPGLALFYGGMVRKKNV
IATITQSVGVFAVVSLVWFVAGYSLAFGKNESAGLQPFIGSLDMLFLNGVSLKTANALLP
GIPEFLFISFQMTFAIITPALITGAFAERFKYSALLLFTALWSLLVYAPICHWVWGGGFL
GSAGVLDFAGGAVVHVNSGVAGLVCAIFLGRRKGYGTEVITAHNPVLTMIGASLLLVGWI
GFNAGSAGAANDLMGVALLNTILAAAAAALTWKVVEYIEKKKVSLIGVLSGVVAGLVAIT
PAAGFVDPKGAVIIGLIAGPACYASSVWIKKLLRYDDSLDAFGIHGAGGLIGALLTGVFA
TTAINSLSEGANVGAQALGLLWTIVYSAVGTLIILFICKFTTGLRVSEAEEAAGLDTSLH
GEALEH