Protein Info for A4249_RS09965 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: glycoside hydrolase family 97 protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 688 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF14508: GH97_N" amino acids 35 to 282 (248 residues), 210.6 bits, see alignment E=3.6e-66 PF10566: Glyco_hydro_97" amino acids 287 to 577 (291 residues), 348.3 bits, see alignment E=5e-108 PF14509: GH97_C" amino acids 579 to 679 (101 residues), 94.6 bits, see alignment E=5.3e-31

Best Hits

KEGG orthology group: K01187, alpha-glucosidase [EC: 3.2.1.20] (inferred from 68% identity to bsb:Bresu_2907)

Predicted SEED Role

"Alpha-glucosidase (EC 3.2.1.20)" in subsystem D-Galacturonate and D-Glucuronate Utilization or Maltose and Maltodextrin Utilization (EC 3.2.1.20)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.20

Use Curated BLAST to search for 3.2.1.20

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A168NLJ7 at UniProt or InterPro

Protein Sequence (688 amino acids)

>A4249_RS09965 glycoside hydrolase family 97 protein (Brevundimonas sp. GW460-12-10-14-LB2)
MMQRRSFLALGGVSILALGATGARAQTAPNHARASSPGGVLTVEAFTDNDGRPMYSVLRQ
GRVVVAPSKLGFLLTDAPAIERGLTLTAGQPVTVDDTWEQPWGERQFIRNHYNEWRVAYA
ETGGLRRRVDVVFRLYDDGLGFRYEFPQQAGLTTVRIGSEITEFNLAENGEALWCPAWEW
NREEYLYSRTPIDAVGSAQTPMTVRGQSGLHVSIHEAACIDYAGMNLRRSEETKFRAQLT
PGLTNAAVVRAAPFNTPWRTLQVSDSAAGLLDSSLILNLNEPNKLGDVSWFKPMKYVGVW
WEMHLDLKTWNSGPKHGATTENAIKHIDFAAKHGLGGVLVEGWNKGWDGQWFANGADFSF
TEAYPDFDIEAVCAHARSKGVQLIGHHETGGNAFHYEQQLEPAMALYERLGVHSVKTGYV
ADAQGARVAGPDGQMVMAWHESQAMAQHHMRVVEAGYRHKVAVNAHEPFKDTGLRRTYPN
IISREGQRGMEYSAWGNPGNPPEHEPNLVFTRLLAGPMDYTPGIFGMETRSPGGVQTTWA
KQLALYVVIYSPIQMAADLLVNYEANPGPFQFIKDVPVDWSESRTLDAAMGDYVVTVRKQ
RGTDVWALGAVTDEHPRVLKAPLDFLDAGRRYRAEIYRDGPNADYRGKREDIVIEQREVT
SSDTLTLALAPGGGQAIRFVPIGRARRG