Protein Info for A4249_RS09960 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: LacI family DNA-binding transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 337 PF00356: LacI" amino acids 8 to 49 (42 residues), 46.1 bits, see alignment 6.6e-16 PF00532: Peripla_BP_1" amino acids 69 to 283 (215 residues), 71.7 bits, see alignment E=1.4e-23 PF13407: Peripla_BP_4" amino acids 80 to 288 (209 residues), 52 bits, see alignment E=1.5e-17 PF13377: Peripla_BP_3" amino acids 179 to 335 (157 residues), 115.5 bits, see alignment E=5.7e-37

Best Hits

KEGG orthology group: None (inferred from 82% identity to bsb:Bresu_2906)

Predicted SEED Role

"Maltose operon transcriptional repressor MalR, LacI family" in subsystem Maltose and Maltodextrin Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A160HY06 at UniProt or InterPro

Protein Sequence (337 amino acids)

>A4249_RS09960 LacI family DNA-binding transcriptional regulator (Brevundimonas sp. GW460-12-10-14-LB2)
MSRKTTRLEDIARLAGVSIATASRALNDSPAVNDRTKQTIWKLAKEHDYPFRRHMPAGPI
GAQGTIALVVPRPQGREGRLSDPFFLELLAGVGEAARERGCDLLMSHISPANYDELSAAL
NTSRADGVIFLGQSSLHSAFNRLVDADHRFVVWGAELPDQDYCSIGSDNISGGRRATLHL
ARLGRKRIVFLGDLDPPEAMQRHRGYLDAMSQSALDVDADLIVPAHFEVESAEAAVDALI
RRGLDFDGVVAASDQIALGAVRALLHAGVEVPGQVSVIGFDNVPFSRYSRPALSTIAQDT
MKAGRLMVSKLLDHGGAAAGRSERVPTELIVRETCGG