Protein Info for A4249_RS09815 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: nucleoside transporter C-terminal domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 424 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details transmembrane" amino acids 32 to 52 (21 residues), see Phobius details amino acids 98 to 123 (26 residues), see Phobius details amino acids 141 to 166 (26 residues), see Phobius details amino acids 178 to 201 (24 residues), see Phobius details amino acids 209 to 231 (23 residues), see Phobius details amino acids 267 to 295 (29 residues), see Phobius details amino acids 304 to 318 (15 residues), see Phobius details amino acids 326 to 346 (21 residues), see Phobius details amino acids 360 to 384 (25 residues), see Phobius details amino acids 397 to 422 (26 residues), see Phobius details PF01773: Nucleos_tra2_N" amino acids 11 to 84 (74 residues), 63.5 bits, see alignment E=3.2e-21 PF07670: Gate" amino acids 103 to 202 (100 residues), 49 bits, see alignment E=1.1e-16 PF07662: Nucleos_tra2_C" amino acids 211 to 415 (205 residues), 220.9 bits, see alignment E=2.4e-69

Best Hits

KEGG orthology group: K03317, concentrative nucleoside transporter, CNT family (inferred from 86% identity to bsb:Bresu_2819)

Predicted SEED Role

"Nucleoside permease NupC" in subsystem Deoxyribose and Deoxynucleoside Catabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A160HZH9 at UniProt or InterPro

Protein Sequence (424 amino acids)

>A4249_RS09815 nucleoside transporter C-terminal domain-containing protein (Brevundimonas sp. GW460-12-10-14-LB2)
MFSLLNLQSLLGLVVIVAVCWAISENRKAFPWRLTIGAILVQAGLVLALFAIPGSQAVLA
AVTGAVDGLAVATTEGTKFVFGYLAGGDQPYAVSNQGALFTFAFQVLPLILVISALSALL
WHWKILKWITLGFGFLFQKTMGLGGASALAVAANIFLGMIESPIVIRAYLDKLTRSEIFL
MMVVGLATVAGSTMVAYATILSPVLPNAAGHVLVASIVSAPAGVLLARIIIPEKEGMGGA
VADYDSALKYDSAIDAIVKGTSDGLMVVLNISAVLIVFVALVALVNVMLGGFVVFDAPLT
VERMLGWIFAPVAWLIGVEWKDADVAGWLLGVKLTLTEFVAFIDLGKVPAAEMTERTRML
MTYALCGFANIGSVGITVTGLSVLMPERREEVLGMVWKGLFAGFLATLMTASVVGAMPAA
VFGF