Protein Info for A4249_RS08485 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: Na+/H+ antiporter subunit C

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 114 signal peptide" amino acids 1 to 18 (18 residues), see Phobius details transmembrane" amino acids 27 to 47 (21 residues), see Phobius details amino acids 75 to 98 (24 residues), see Phobius details PF00420: Oxidored_q2" amino acids 6 to 108 (103 residues), 73.8 bits, see alignment E=3.9e-25

Best Hits

Swiss-Prot: 75% identical to PHAC1_RHIME: Probable K(+)/H(+) antiporter subunit C (phaC) from Rhizobium meliloti (strain 1021)

KEGG orthology group: K05560, multicomponent K+:H+ antiporter subunit C (inferred from 75% identity to rcp:RCAP_rcc02131)

Predicted SEED Role

"Na(+) H(+) antiporter subunit C" in subsystem Sodium Hydrogen Antiporter

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A168NXU3 at UniProt or InterPro

Protein Sequence (114 amino acids)

>A4249_RS08485 Na+/H+ antiporter subunit C (Brevundimonas sp. GW460-12-10-14-LB2)
MMELVLALAIGVLSASGVWLLLRPRTFQVIMGLSLLSYAVNIFIFAMGRLRSGAPPVLAG
DVSDPARYTDPTPQALVLTAIVISFALTALFLVVILAARGITGNDHVDGKEPDA