Protein Info for A4249_RS08410 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: D-alanyl-D-alanine carboxypeptidase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 496 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details PF00768: Peptidase_S11" amino acids 31 to 258 (228 residues), 209.1 bits, see alignment E=1e-65 PF13354: Beta-lactamase2" amino acids 44 to 190 (147 residues), 36.1 bits, see alignment E=7e-13 PF05036: SPOR" amino acids 419 to 493 (75 residues), 27.1 bits, see alignment E=6.5e-10

Best Hits

Predicted SEED Role

"D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4)" in subsystem Peptidoglycan Biosynthesis (EC 3.4.16.4)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.4.16.4

Use Curated BLAST to search for 3.4.16.4

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A160HZK3 at UniProt or InterPro

Protein Sequence (496 amino acids)

>A4249_RS08410 D-alanyl-D-alanine carboxypeptidase family protein (Brevundimonas sp. GW460-12-10-14-LB2)
MIAFLRRGLFAVLALSLVLGANVRPIEAQTAYSAQENSRYAAIVIDAATGEVLFARNADS
RRYPASLTKMMTLYLTFEALSQGKANVNDVLTISPRAASQPPSKLGLAAGQTITLDNAMR
ATAVRSANDMALAIGEHIGGSEARFTNMMTQKAAQLGMTQTRYYTANGLPDARQVTSARD
QAILARAIMRDFPQYYSYFGLHDWAYNGRNYRNTNGLLPTGRGYDGMKTGYTNASGYNLA
ASAVRDGRRLITVVLGGRSTASRNAHVAELMDTGFEVERRRAQGERIQVAQTFFEQRGFG
VGSAIADAPIAYASVNDDEDGVGAESTAVAYTAAPAPAALPTRVAPAPSERAASQRAAAA
LPPIGSAPTASAAPRAPRNVTASLNGAPANAAVAPSTTPRRSASSATREPARAAARTPAG
RWAVQVGAFREEKVATDWLTEVNRRFRDQFATAERNVQTAGDWYRSRFVGLTETGAKSAC
EALAARRVTCMVIGPD