Protein Info for A4249_RS08050 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: elongation factor Tu

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 396 TIGR00485: translation elongation factor Tu" amino acids 1 to 396 (396 residues), 745.5 bits, see alignment E=1.1e-228 PF00009: GTP_EFTU" amino acids 10 to 204 (195 residues), 216.1 bits, see alignment E=5e-68 TIGR00231: small GTP-binding protein domain" amino acids 14 to 148 (135 residues), 54.1 bits, see alignment E=1.6e-18 PF03144: GTP_EFTU_D2" amino acids 227 to 296 (70 residues), 70.5 bits, see alignment E=2e-23 PF03143: GTP_EFTU_D3" amino acids 300 to 394 (95 residues), 133.2 bits, see alignment E=6.3e-43

Best Hits

Swiss-Prot: 93% identical to EFTU2_CAUSK: Elongation factor Tu 2 (tuf2) from Caulobacter sp. (strain K31)

KEGG orthology group: None (inferred from 98% identity to bsb:Bresu_1794)

Predicted SEED Role

"Translation elongation factor Tu" in subsystem Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (396 amino acids)

>A4249_RS08050 elongation factor Tu (Brevundimonas sp. GW460-12-10-14-LB2)
MAKEKFERTKPHCNIGTIGHVDHGKTTLTAAITMTLAKAGGAKAMNYADIDAAPEEKARG
ITINTAHVEYETANRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHI
LLARQVGVPALVVFMNKVDLVDDEELLELVEMEVRELLSSYQFPGDDIPITKGSAKAATD
GVNPEIGEQRVLALMETVDAYIPQPERPVDLPFLMPVEDVFSISGRGTVVTGRVEKGIVK
VGEEVEIVGIRPVQKTTCTGVEMFRKLLDQGQAGDNVGVLLRGTKREDVERGQVLCKPGS
ITPHTKFLAEAYILTKEEGGRHTPFFTNYRPQFYFRTTDVTGIVHLKEGVEMIMPGDNAE
LNVELITPIAMDQGLRFAIREGGRTVGAGVVAKIVE