Protein Info for A4249_RS07860 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: putative 2OG-Fe(II) oxygenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 494 PF13181: TPR_8" amino acids 74 to 102 (29 residues), 14.6 bits, see alignment (E = 7.8e-06) amino acids 112 to 138 (27 residues), 12.3 bits, see alignment (E = 4.3e-05) PF13759: 2OG-FeII_Oxy_5" amino acids 398 to 490 (93 residues), 75.4 bits, see alignment E=1e-24

Best Hits

KEGG orthology group: None (inferred from 44% identity to cse:Cseg_3292)

Predicted SEED Role

"TPR domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A168NJ25 at UniProt or InterPro

Protein Sequence (494 amino acids)

>A4249_RS07860 putative 2OG-Fe(II) oxygenase (Brevundimonas sp. GW460-12-10-14-LB2)
MTAGVQARVEGAKALAAAGQLNAALEMLAPMAQQADAPWQALSVQADLMKRVGRLEESAA
LSQRLVEVRPHSIPAWHNLASTLGDLGRAAEAEVACRAAMSIGGHAPETSLVLARALQAQ
SRFDEAEDAYRKALLRRPGYGDALRDLSQLIWMRDADLETACAPLDAAIAVSPATPLLRQ
IKAKLLEYAGEGEGAYRTLVAGPLDGPGELAAAQACLTWGPRRALDHANRAAALAGGEVP
AIMVTQAECLLALGEAEAALVPIEALRAREPLNQHVLAFQATAWRMLGDVRYGRLYDYDA
FVRPYRLEAPDGWASLEAYLVDLARALHDLHTLKTHPVGQSLRGGSQTTAPLAQGEDPAI
RAFFQAIDKPIRDYMAAVGRGDDPLRARNTGDYRIQGSWSVRLRPNGFHADHIHSNGWLS
SACHIELPPAVQGERREGWLRFGAPPGLPSLAAEHYVQPRPGTLVLFPSYMWHGTQPFGG
EASRLTLAFDVVPA