Protein Info for A4249_RS07735 in Brevundimonas sp. GW460-12-10-14-LB2
Annotation: altronate dehydratase family protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K01685, altronate hydrolase [EC: 4.2.1.7] (inferred from 59% identity to ppg:PputGB1_2948)MetaCyc: 57% identical to D-arabinonate dehydratase (Herbaspirillum huttiense)
Arabinonate dehydratase. [EC: 4.2.1.5]
Predicted SEED Role
"Altronate dehydratase (EC 4.2.1.7)" (EC 4.2.1.7)
MetaCyc Pathways
- D-galacturonate degradation I (4/5 steps found)
- superpathway of hexuronide and hexuronate degradation (7/10 steps found)
- D-arabinose degradation III (4/6 steps found)
- D-arabinose degradation IV (3/6 steps found)
- superpathway of microbial D-galacturonate and D-glucuronate degradation (13/31 steps found)
- superpathway of pentose and pentitol degradation (11/42 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 4.2.1.5 or 4.2.1.7
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A160HZW6 at UniProt or InterPro
Protein Sequence (499 amino acids)
>A4249_RS07735 altronate dehydratase family protein (Brevundimonas sp. GW460-12-10-14-LB2) MSRVLILNPADDVAIALDDIASGDTLDGLTAPARADIATGHKIARHAVEAGGLVRRYGQV IGRAKAAIAAGDHVHVHNLAMAEDGREAEVGADLRPPAALSGATFSGIVRPDGRVGTRNY IGVLTSVNCSATVARRIADAFPDSILPAGVDGVVAFTHQGGCGGSSLSSDVTLLQRTLAG YARHPNFHSILIVGLGCEANQIPAWLANEGLQSGSRLRALTIQEAGGTARAIEAGIEIVR DLVTEAAQVQRQPVSASRLTVGLQCGGSDSWSGVTANPALGAAVDLVVAHGGSAMLSETP EIWGAEHLLLRRAASQNVAEKLNARLAWWRDYADRHQMELNNNPSPGNLKGGLTTILEKS LGAVAKSGSTPLNDVIGYAEPLQAKGLSFMDSPGYDPCSATGQIASGANLIVFTTGRGSV FGAKPAPSIKVASNARLANWMDEDMDIDASPVLTGTSLVEVGKVIFRKMLDVASGEPSKS EALGIGDNEFVPWQVGAYL