Protein Info for A4249_RS06770 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 543 transmembrane" amino acids 6 to 24 (19 residues), see Phobius details amino acids 36 to 60 (25 residues), see Phobius details amino acids 66 to 85 (20 residues), see Phobius details amino acids 92 to 113 (22 residues), see Phobius details amino acids 119 to 140 (22 residues), see Phobius details PF00512: HisKA" amino acids 169 to 233 (65 residues), 52.3 bits, see alignment E=7.1e-18 PF02518: HATPase_c" amino acids 280 to 394 (115 residues), 102.7 bits, see alignment E=2.4e-33 PF00072: Response_reg" amino acids 418 to 530 (113 residues), 85.6 bits, see alignment E=4e-28

Best Hits

KEGG orthology group: None (inferred from 63% identity to bsb:Bresu_0843)

Predicted SEED Role

"sensor histidine kinase/response regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (543 amino acids)

>A4249_RS06770 ATP-binding protein (Brevundimonas sp. GW460-12-10-14-LB2)
MLRWVPLWLAAAVLVQAFELWAMAPFRRAEASQSPLSVFVALASTTVMATTYAAMALMVW
STNHPALVTLAALTMVGGLLTNVASGIASRRIFFIGGSPYLAALALMPAIKVIQGDTRGV
VVMTLSAVLFVGMVLNIYWRVHGSREAEVKSRAEAETRLEQAQAAMADRAAMAAIVSHEL
RTPVSAILAGAHVIRDGKSPEHRQETADLIIDAGRLMTGMLNDLLDHSKMEAGAMAMESR
DFELGDLMRDTVRFWAAPAADKGLTLDMSGVDSEAVWLRGDPYRLRQIINNLVSNAIKFT
STGAIRLEASAPRGDGKHCLTLTVTDQGAGIAPEAMSRLFTPFAQGSAEVARTYGGTGLG
LTVSRELARLMGGDLTVESTPGQGAAFTLCVDLPAGQPTQALDGQETAAPVLARRLRVLA
VDDHEINRRTISLVLQPLDVDLTTASDGHLALALLSEKVFDVVLMDVNMPGIDGNETTRR
LRASDGPNAAAPVIGFSAGTETEQVQACYAAGMTDWLAKPLEPKKLYDALHRATSAAAQA
KAA