Protein Info for A4249_RS06545 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: ferredoxin--NADP reductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

Best Hits

Swiss-Prot: 55% identical to FENR_RHOCA: Flavodoxin/ferredoxin--NADP reductase (fpr) from Rhodobacter capsulatus

KEGG orthology group: K00528, ferredoxin--NADP+ reductase [EC: 1.18.1.2] (inferred from 82% identity to bsb:Bresu_2459)

Predicted SEED Role

"ferredoxin-NADP reductase"

MetaCyc Pathways

ethene biosynthesis V (engineered) (18/25 steps found)
photosynthetic 3-hydroxybutanoate biosynthesis (engineered) (18/26 steps found)
oxygenic photosynthesis (11/17 steps found)
1-butanol autotrophic biosynthesis (engineered) (18/27 steps found)
NADPH to cytochrome c oxidase via plastocyanin (thylakoid membrane) (1/4 steps found)
photosynthesis light reactions (1/4 steps found)
superpathway of photosynthetic hydrogen production (2/6 steps found)

KEGG Metabolic Maps

Photosynthesis

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.18.1.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A160HYT8 at UniProt or InterPro

Protein Sequence (271 amino acids)

>A4249_RS06545 ferredoxin--NADP reductase (Brevundimonas sp. GW460-12-10-14-LB2)
MTDAALSPAPVKASPFNELEVLWVRHWTDSLFSFGVKRPEDFRFRSGEFVMIGLPGEDGG
KPVLRAYSIASPCWAEELEFFSIKVADGPLTSRLQKIQPGDTVLMGKKPTGTLVLDALTG
GERLFLIGTGTGLAPWLSVARDPETYSRFGHVYVIHTVRSVADLAYRDFFTREIHDDPLI
GEEAQAQLTYYPTVTREDFETPGRITDRIKSGDFFRDLGLPEGFDPARDRAMLCGSMAMI
KEAGELLETYGLKEGSNAEPADYVLERAFVG