Protein Info for A4249_RS06185 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: ComEC/Rec2 family competence protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 728 transmembrane" amino acids 39 to 57 (19 residues), see Phobius details amino acids 63 to 80 (18 residues), see Phobius details amino acids 89 to 107 (19 residues), see Phobius details amino acids 286 to 312 (27 residues), see Phobius details amino acids 323 to 342 (20 residues), see Phobius details amino acids 353 to 381 (29 residues), see Phobius details amino acids 387 to 408 (22 residues), see Phobius details amino acids 428 to 450 (23 residues), see Phobius details amino acids 460 to 484 (25 residues), see Phobius details amino acids 492 to 515 (24 residues), see Phobius details amino acids 525 to 545 (21 residues), see Phobius details PF13567: DUF4131" amino acids 63 to 213 (151 residues), 60 bits, see alignment E=2.5e-20 PF03772: Competence" amino acids 263 to 545 (283 residues), 198.7 bits, see alignment E=1.2e-62 TIGR00360: ComEC/Rec2-related protein" amino acids 282 to 477 (196 residues), 63.9 bits, see alignment E=1.1e-21

Best Hits

KEGG orthology group: K02238, competence protein ComEC (inferred from 70% identity to bsb:Bresu_2145)

Predicted SEED Role

"ComEC/Rec2-related protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A160HYR3 at UniProt or InterPro

Protein Sequence (728 amino acids)

>A4249_RS06185 ComEC/Rec2 family competence protein (Brevundimonas sp. GW460-12-10-14-LB2)
MGEGSVSEALIRPDAAKPTPAARLRAWLDAEVAAQTLRWRLWAPVAFGAGGGIYFALRAE
PVLWPLLLGAALAFGLWVVARRRGGSRRLTWLLLILACVTGGLAAAKVRTEAVAAPIAPA
LSEPTVIEAWVVDVDSPGQQGARVVIAPVWIRGLTPEQTPVRLRATVRGDPPRPGEAIRL
FGILNPPPAPASPGAYDFGRNAFFQGMGGVAFALGDTRTAELAPPPWRLRLEMVVNAARF
ALAERIVARLGQRTGGIAAAMTTSHETWISQEDMDVMRDSGLAHILSVSGLHMAIVGGFV
FFAVRLGVAAWPWLALRVHGKKVAALAGLTAVGVYLVVSGAPPPAERAATTASIAFLAIL
LDRQAVTMHGLAVAAFIVLAIQPEAIVTPGFQMSFAATAALVALVEAWPKRPREISAPWP
ILAVQRLGGWLTAAVAASVVAGLATGPFAMQHFNRTAMYGLLANLGTSPVADFILMPALA
LGAALEPLGLGGPFLAVAGWGVDLMLAIGAWTAGLPGAVRTVASAPNYVLPVAFLGVLFV
CLWQGRLRWLGLPFAAAVLIWPREPTPDLWLGDGGTNAAFHRDEAAVVVRPGVREFAVDL
WSRRRGLAMTDRSETGWVCDRFSCRPEADEAGPVAIWWGRKSPSSDQMEALCRAAPVVSV
RAVVSSIPSACQDRLVLDSVDFARGGAVELWRVSSDEPNRWRAVWTADVRGDRPWTRQSD
PDVSDSGA