Protein Info for A4249_RS05915 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: peptide-methionine (R)-S-oxide reductase MsrB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 167 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details TIGR00357: methionine-R-sulfoxide reductase" amino acids 44 to 166 (123 residues), 146.9 bits, see alignment E=1.8e-47 PF01641: SelR" amino acids 49 to 165 (117 residues), 149.9 bits, see alignment E=1.6e-48

Best Hits

KEGG orthology group: K07305, peptide-methionine (R)-S-oxide reductase [EC: 1.8.4.12] (inferred from 66% identity to bsb:Bresu_1907)

Predicted SEED Role

"Peptide methionine sulfoxide reductase MsrB (EC 1.8.4.12)" (EC 1.8.4.12)

Isozymes

Compare fitness of predicted isozymes for: 1.8.4.12

Use Curated BLAST to search for 1.8.4.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A160HZ52 at UniProt or InterPro

Protein Sequence (167 amino acids)

>A4249_RS05915 peptide-methionine (R)-S-oxide reductase MsrB (Brevundimonas sp. GW460-12-10-14-LB2)
MTQSLIPNRRGLLMSAGALALSACSPETSEAGEGQYAASPYRRVSDADWRRRLGDASWRV
MRHEGTERPYSSPLNDQHARGTFVCKGCDLPLFRSQWKFDSHTGWPSFYDVIAANIGKKR
DLAIGIPRTEYHCARCLGHQGHVFDDGPRPTGLRYCNNGVALKFVSA