Protein Info for A4249_RS05825 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: DDE-type integrase/transposase/recombinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 551 PF09039: HTH_Tnp_Mu_2" amino acids 59 to 155 (97 residues), 24.2 bits, see alignment E=4.4e-09 PF00665: rve" amino acids 169 to 291 (123 residues), 48.4 bits, see alignment E=1.5e-16 PF09299: Mu-transpos_C" amino acids 389 to 441 (53 residues), 47 bits, see alignment 3.1e-16

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A160HWK3 at UniProt or InterPro

Protein Sequence (551 amino acids)

>A4249_RS05825 DDE-type integrase/transposase/recombinase (Brevundimonas sp. GW460-12-10-14-LB2)
MSVDLLDAEEPDEPDAAWRAAAEARHVLLPLAQMGRKRRAAVDAAAAQLNISTAKAYRMI
ALLKEDDRASALLPEKRGRSPGSSMYDAAVEAIILEVLQKDYMSGQQPRVAHVLATVRAR
CRKAGLKQPGRKGLMARVQALDLHDRLKARRGKNAAEIATPRPGEFVAERPNQVWLIDHT
EGDIILVDRRFRLPIGRPTVTLIIDAYTRMCVGCYVSLGKPSRIQSGMALLRAFLPKEGL
LEQAGQDWDWPCQGFPEIVHSDNGSDFRSDAFRRGLITYGITPKFRPVREPRYGALIERY
IGTTMGELHLVPGTTFSNVSDRGEYDSEAKAVMSLDGFERWLFLQIGRYHISPHRGIGGF
TPISRWKESVNAGFRQKDAPPGAAVDIMLAFLPSDRRKLRNTGIHFKSLRYWSAWLGAAV
RRGGVAVDLRYDPRDMSFVWVEWEGRWERVHLYKRQAPFTLREHELALKALREAAVATVD
EDMIHAKREESEALIASEAATTKRARRRLEHGERSLEVAQTIYGEPEPAKPIITDLVFSK
LAKSKRIVEEW