Protein Info for A4249_RS05605 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: cyclopropane-fatty-acyl-phospholipid synthase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 406 PF02353: CMAS" amino acids 130 to 401 (272 residues), 291.1 bits, see alignment E=2.4e-90 PF13489: Methyltransf_23" amino acids 174 to 298 (125 residues), 46.5 bits, see alignment E=1e-15 PF13847: Methyltransf_31" amino acids 188 to 301 (114 residues), 33.8 bits, see alignment E=8.7e-12 PF13649: Methyltransf_25" amino acids 193 to 287 (95 residues), 54.1 bits, see alignment E=6.2e-18 PF08241: Methyltransf_11" amino acids 194 to 288 (95 residues), 46.8 bits, see alignment E=1.1e-15 PF08242: Methyltransf_12" amino acids 194 to 288 (95 residues), 39.8 bits, see alignment E=1.8e-13

Best Hits

KEGG orthology group: K00574, cyclopropane-fatty-acyl-phospholipid synthase [EC: 2.1.1.79] (inferred from 74% identity to bsb:Bresu_1922)

MetaCyc: 48% identical to cis-vaccenate 11-methyltransferase (Cereibacter sphaeroides)
2.1.1.-

Predicted SEED Role

No annotation

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.79

Use Curated BLAST to search for 2.1.1.79

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A160HYF8 at UniProt or InterPro

Protein Sequence (406 amino acids)

>A4249_RS05605 cyclopropane-fatty-acyl-phospholipid synthase family protein (Brevundimonas sp. GW460-12-10-14-LB2)
MSVAHADIEAVASRTPRVFAMLLRLLAANWTFGRLTVQLPNGETHVLQGKQPGPSGMMTV
RNYRFARRVLAAGDIGFAEGYIAGEWDSPHLAGLLETLVDNYDHIRRLFDGNLIMWVVNW
LSHRTNRNSKTGSKKNIHAHYDLGNAFYSQWLDGTMTYSSARFSRDSEALEAAQREKYAA
LARMMDLRPGMSVLEIGCGWGGFAEFAAREIGADVTGITISKEQHYFARQRMFNAGLSDR
ADIQLIDYRDVQGRFDRVASIEMFEAVGMEYWPAYFGKVHDVLRPGGKAGLQIITIQDDL
FDEYNARTDFIQKYVFPGGMLPSEERLAPVVSKAGLSWQSVERFGLDYAATLKLWDERFQ
ASWGEISKLSGFDERFRRLWRFYLAYCEAGFRSRRTDVIQLSLSRP