Protein Info for A4249_RS04755 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: TatD family hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 260 TIGR00010: hydrolase, TatD family" amino acids 2 to 253 (252 residues), 253.3 bits, see alignment E=1.2e-79 PF01026: TatD_DNase" amino acids 3 to 253 (251 residues), 273.1 bits, see alignment E=1.1e-85

Best Hits

Swiss-Prot: 39% identical to DTD3_SYNY3: D-aminoacyl-tRNA deacylase (dtd3) from Synechocystis sp. (strain PCC 6803 / Kazusa)

KEGG orthology group: K03424, TatD DNase family protein [EC: 3.1.21.-] (inferred from 79% identity to bsb:Bresu_1992)

Predicted SEED Role

"Putative deoxyribonuclease YcfH" in subsystem YcfH

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.21.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A168NEY2 at UniProt or InterPro

Protein Sequence (260 amino acids)

>A4249_RS04755 TatD family hydrolase (Brevundimonas sp. GW460-12-10-14-LB2)
MLIDSHVNLHAPQFDEDRDAVIARAREAGVGLMVEISDKLTTFEATHGIAMANPAIWCTV
GVHPHEAKDAADLTAATLIELAQRPKVVGIGECGLDFHYDFSPREVQAAVFRQHVAAARE
TGLPLVIHTREADDVMASILREEYAAGPFKMLMHCYTSGAELAKIAAEMGAWFSVSGIAT
FKAAEDVRAVIRDMPGDRIIVETDCPYLAPIPHRGRRNEPAYIGHVLDKLAEIRGWSAEE
ADRLTTEAFFGLFDRIPRPA