Protein Info for A4249_RS04575 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: Fe-S cluster assembly protein SufB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 488 TIGR01980: FeS assembly protein SufB" amino acids 16 to 479 (464 residues), 631.6 bits, see alignment E=3.2e-194 PF19295: SufBD_N" amino acids 152 to 209 (58 residues), 35.9 bits, see alignment 6.3e-13 PF01458: SUFBD" amino acids 226 to 459 (234 residues), 240.4 bits, see alignment E=1.9e-75

Best Hits

Swiss-Prot: 66% identical to Y074_SYNY3: UPF0051 protein slr0074 (slr0074) from Synechocystis sp. (strain PCC 6803 / Kazusa)

KEGG orthology group: K09014, Fe-S cluster assembly protein SufB (inferred from 95% identity to bsb:Bresu_2180)

Predicted SEED Role

"Iron-sulfur cluster assembly protein SufB" in subsystem Staphylococcal phi-Mu50B-like prophages

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A160HW46 at UniProt or InterPro

Protein Sequence (488 amino acids)

>A4249_RS04575 Fe-S cluster assembly protein SufB (Brevundimonas sp. GW460-12-10-14-LB2)
MAAVKETIDAVAALEKYEHGFTSDIETEYAPKGLSAEIVRFISEKKGEPEWMLEWRLAAY
ERWLAMEEPTWAAVRYEPVDYQDLFYYAAPKAKEGPKSLDEVDPEILEIYKKLGIPLKEQ
EVLAGVQGAPKVAVDAVFDSVSVVTTFKEELAKVGVIFMPISEALREYPDLVRQYLGSVV
PVSDNYFAALNSAVFSDGSFVYIPPGVKCPMELSTYFRINASQTGQFERTLIIADKGAYV
SYLEGCTAPMRDENQLHAAVVEIVALDDAEVKYSTVQNWYPGDAEGKGGIYNFVTKRADC
RGDRSKVSWTQVETGSAVTWKYPSCVLKGEESSGEFYSIAITNGHQQADTGTKMIHLGKN
SKSRIIAKAVSAGRSDSTYRGLVSVHPKATGVRNFTQCDSLLIGKECGSHTIPYIEARNG
SAQLEHEATTTRLSDDQLFYAQQRGLSQEEAVALLVNGFVRDVMQKLPMEFAVEAQKLVA
ISLEGSVG