Protein Info for A4249_RS04085 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: ribonuclease E/G

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 TIGR00757: ribonuclease, Rne/Rng family" amino acids 14 to 465 (452 residues), 506.9 bits, see alignment E=2.2e-156 PF10150: RNase_E_G" amino acids 164 to 434 (271 residues), 334.4 bits, see alignment E=5.5e-104 PF20833: RNase_E_G_Thio" amino acids 447 to 530 (84 residues), 80.5 bits, see alignment E=8.2e-27

Best Hits

Predicted SEED Role

"Cytoplasmic axial filament protein CafA and Ribonuclease G (EC 3.1.4.-)" in subsystem Bacterial Cell Division or RNA processing and degradation, bacterial (EC 3.1.4.-)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.4.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A160HXV5 at UniProt or InterPro

Protein Sequence (900 amino acids)

>A4249_RS04085 ribonuclease E/G (Brevundimonas sp. GW460-12-10-14-LB2)
MSKTMLIDAAHPEETRVAIVDGRKIEEFDFESRAKRQLRGNIYLAKVTRVEPSLQAAFIE
YGGNRHGFLAFNEIHPDYYQIPVADREAIMAEAHDDEDEDDLDRESTGDDVDPESALADE
ERLKRRLMRRYKIQDVIKRRQILLVQVVKDERGAKGAALTTWLSLAGRYCVLMPNTGKGG
GISRKITNTSDRRRLKSAVSALEVPKGMGLIIRTAGAKRTKAEIKRDYQYLLRLWETIRE
TTLASHAPSVIYEEENLVRRAVRDMFDKDFDGIQVEGVEGFKEARDFMRVLMPAQAKKVH
LYRGSRPLFAANGIEELLTQIHQPVVPLKSGGYLVINQTEALVAIDVNSGRATKERNVEQ
TAFKTNMEAAEEAARQLRLRDLAGLVVIDFIDMDEGKNNRAVERVLKEALSSDRARIQMG
RISPFGLMEISRQRRRLGVIEGATEACPHCQGTGRIRSAESAALMTLRAVDIEAGKNGAG
VVVLKVCTAVGLYILNHKRAYLQSLLERRGLNVIVQIDDSLGQGEHNIERTETNEDFVAP
EIEMPNLDDDFDASLYEDEDEEDDEEIIVDDDDDTVESLDREDSDDDEPRERSERHEGSR
DRGRGRNRRRRGGRRDEETSDVEAVDTVSADDASDDEEDENGRRRRRGRRGGRRVREDGE
RDVYTWVRGRTPSLDDPYVWFDPLNPGRSEGRPERGERPERAERPAVAQSEGEGLDVVPG
EGSGEEGGRSRRRRRRGRGRGDGSVSHEIKVENRATNEGMPPDGSPETPMAVMVEPTEAV
ETAAPAIAPEPQRRRVRRKSASANVEIAAEPHPDTAIEPNEATVQGAPAELDVTPHEALA
AEPAEVAPVAAPTAVPVTEAVLAEPFVAPTPEIDVQAIIAEDPNQIVAPPEKPKRGWWRR