Protein Info for A4249_RS04075 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: thioredoxin domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 259 transmembrane" amino acids 25 to 46 (22 residues), see Phobius details PF18312: ScsC_N" amino acids 51 to 76 (26 residues), 37.2 bits, see alignment (E = 2.9e-13) PF13462: Thioredoxin_4" amino acids 98 to 255 (158 residues), 80.3 bits, see alignment E=2.9e-26 PF01323: DSBA" amino acids 109 to 247 (139 residues), 73 bits, see alignment E=4.5e-24

Best Hits

KEGG orthology group: None (inferred from 61% identity to bsb:Bresu_2195)

Predicted SEED Role

"27kDa outer membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A168NE08 at UniProt or InterPro

Protein Sequence (259 amino acids)

>A4249_RS04075 thioredoxin domain-containing protein (Brevundimonas sp. GW460-12-10-14-LB2)
MTDDAPTPAPEPKTAKPGWLSGGRAGYLALGLSVIALGFSAAPYLTGGSNVRAYLLEHPE
VLQEAQMALQTKDAEAAVEETNQAAAANAGLLAPDARDPAFGPANAKVTVIEFFDFRCPG
CKAVAHDYRALMAAHPEVRFVFKDWPILDRGDDITSQYAARAALAAHQQGKYLEVYDALM
TERALSIEAIDAILAAHGLDMARAKAAIAAPDTTRHIADIHTTAAALRLRGTPTFFVNGK
ASPGIDPAEIGKLIEAAKR