Protein Info for A4249_RS03925 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: 50S ribosomal protein L2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 278 TIGR01171: ribosomal protein uL2" amino acids 3 to 273 (271 residues), 407.4 bits, see alignment E=1.5e-126 PF00181: Ribosomal_L2" amino acids 42 to 117 (76 residues), 103.9 bits, see alignment E=3.7e-34 PF03947: Ribosomal_L2_C" amino acids 125 to 250 (126 residues), 193 bits, see alignment E=1.8e-61

Best Hits

Swiss-Prot: 82% identical to RL2_PHEZH: 50S ribosomal protein L2 (rplB) from Phenylobacterium zucineum (strain HLK1)

KEGG orthology group: K02886, large subunit ribosomal protein L2 (inferred from 91% identity to bsb:Bresu_1510)

MetaCyc: 59% identical to 50S ribosomal subunit protein L2 (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"LSU ribosomal protein L2p (L8e)" in subsystem Ribosome LSU bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A160HXS6 at UniProt or InterPro

Protein Sequence (278 amino acids)

>A4249_RS03925 50S ribosomal protein L2 (Brevundimonas sp. GW460-12-10-14-LB2)
MALKHYNPTSPGRRALVLVDRSELHKGRPEKSLTEGLTKSGGRGQGGRIAVRFRGGGAKT
LYRKIDFKRRKWDMVGTVERLEYDPNRTAFIALVTYEDGEKTYIIAPQRLKAGDTIVAGE
KTDVKPGNAMPLRSMPVGTIIHNIEMKPGKGAQLARSAGAYAQLVGRDQGYAQIRLGSGE
LRMVLDGCIATVGAVSNPDHMNQNLGKAGRKRHMGWRPHVRGVAMNPIDHPHGGGEGRTS
GGRTPVTPWGKDTKGTRTRKNKATDKYIIRTRHVKKAR