Protein Info for A4249_RS02840 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: N-succinylarginine dihydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 445 TIGR03241: succinylarginine dihydrolase" amino acids 4 to 443 (440 residues), 562.3 bits, see alignment E=4.3e-173 PF04996: AstB" amino acids 4 to 443 (440 residues), 633.8 bits, see alignment E=7.2e-195

Best Hits

Swiss-Prot: 74% identical to ASTB2_CAUVC: N-succinylarginine dihydrolase 2 (astB2) from Caulobacter vibrioides (strain ATCC 19089 / CB15)

KEGG orthology group: K01484, succinylarginine dihydrolase [EC: 3.5.3.23] (inferred from 87% identity to bsb:Bresu_1342)

Predicted SEED Role

"Succinylarginine dihydrolase (EC 3.5.3.23)" in subsystem Arginine and Ornithine Degradation (EC 3.5.3.23)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.3.23

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A168NC45 at UniProt or InterPro

Protein Sequence (445 amino acids)

>A4249_RS02840 N-succinylarginine dihydrolase (Brevundimonas sp. GW460-12-10-14-LB2)
MISAVEANADGLIGPTHSYAGLSPGNLASSLNKGEASNPRAAVLQGLDKMKTLADLGLPQ
FVLPPHERPNIPFLRTLGFAGSDAQVLERAWRSAPSFAAAACSASPMWAANAATVTPSAD
AADGRVHFTPANLHTNLHRSLEHRQTKRALDALFADASRFAVHDALPAVAHLADEGAANH
VRLCAQHGGRGVNLLVWGREAFEPWDGPFPARQTREASEAIVRRHEAGRPVLAQQSRAAI
AGGTFHNDVVCVGALDTLFFHELAFEDTAATQAAIRRAADGLFEPIFVEVSAADLPLADA
ISSYLFNSMLIQVPGEDRLTLICPTETRDNPRSHAVAQALAASNGPIGRVHYVDVRQSMR
NGGGPACLRLRVVLTEAELAATNPAMRLTDELHARLSDWAGRWYRDELRPADLADPDLLT
ESRGALDELTTILNLGTDFYPFQRG