Protein Info for A4249_RS02590 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: helix-turn-helix transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 476 PF13560: HTH_31" amino acids 11 to 66 (56 residues), 53.5 bits, see alignment 6.1e-18 PF12844: HTH_19" amino acids 12 to 69 (58 residues), 39.1 bits, see alignment 1.6e-13 PF01381: HTH_3" amino acids 15 to 67 (53 residues), 48.8 bits, see alignment 1.4e-16 PF06114: Peptidase_M78" amino acids 192 to 315 (124 residues), 78.3 bits, see alignment E=1.1e-25 PF09856: ScfRs" amino acids 316 to 471 (156 residues), 213.3 bits, see alignment E=4.2e-67

Best Hits

KEGG orthology group: K07110, (no description) (inferred from 75% identity to bsb:Bresu_1694)

Predicted SEED Role

"Transcriptional regulator, XRE family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A168NAM7 at UniProt or InterPro

Protein Sequence (476 amino acids)

>A4249_RS02590 helix-turn-helix transcriptional regulator (Brevundimonas sp. GW460-12-10-14-LB2)
MNAAADRKLFLGARLKRLRRDLGLTQTAMAADLDVSPSYLNHIERNQRPVSAQLLLRLAD
TYDVDLRALNQGGAADEARLTEILTDPLFKGLSAPRHELVQLLEEAPGVADALLRLYQAF
DDGRTRARAAAETGESPIETSPAEWVREYIQSRGNHFPELDQMGEALSDALSAEAPAHAD
GFEPAARHRLAARHDLGVRTLPAEVMVDWTRRYDLHRRRLLLSETLGPSSRAFAIAYQLA
LAEQGPALNALAEASNAPDAPTRSLLKVALTNTLAAATLMPYAAFQRAAEETRYDLARLQ
ARFGVSYEQAAHRLTTLSRPTARGVPFFLMRVDQAGNISKRYAAGAFPFSRFGGACPRWR
LHSAFRTPGRIVTQIIETPDGGRWFTFARTVERQGHDGYGEHHDLAVGLGCELRHAHRLA
YAHGMDLQNPEVTPIGPACRLCHRHPCAERAAAPIDRPLAVDDWSKSVSPYPFGAA