Protein Info for A4249_RS02550 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: dipeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 419 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF01244: Peptidase_M19" amino acids 33 to 394 (362 residues), 394.5 bits, see alignment E=1.8e-122

Best Hits

KEGG orthology group: K01273, membrane dipeptidase [EC: 3.4.13.19] (inferred from 73% identity to bsb:Bresu_2729)

Predicted SEED Role

"putative dipeptidase"

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.13.19

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A168NAD1 at UniProt or InterPro

Protein Sequence (419 amino acids)

>A4249_RS02550 dipeptidase (Brevundimonas sp. GW460-12-10-14-LB2)
MIRRLLSVAVASLALGGAVQAQDAEEARVMEILKTTPLIDGHNDLPWALRQQYGNDVYAV
DLTRNLAASTKLHTDIARLRAGGVGGQFWSVYVPASLTPLEAVEETFEQIDTAKRIIAAH
PDTFGLATTADEVDAVFKSGRIASLIGMEGGYSIDDSLALLREFYRAGARYMTLTHSKTT
TWADSATDAPKWGGLSPSGEAVVKEMNRLGMMVDLSHVSEETMLDAMRVSDAPVIFSHSS
ARAVTDHPRNVPDRVLRMMPQDGGIVMINLAPGFVSEAVRAWNGAKAGEEARLKTLNPGD
PGAVEAGLTAWTAANPTPQATLADVVAHIQHVREVAGIDHVGLGADFDGIGSLPEGMGGV
DAYPRILAALMAAGWSEADIRKIAGENLLRVMREVEAVAASKSGERPSMARLEPASAQN