Protein Info for A4249_RS02540 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: LysR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 291 PF00126: HTH_1" amino acids 3 to 62 (60 residues), 73.7 bits, see alignment E=1.4e-24 PF03466: LysR_substrate" amino acids 88 to 290 (203 residues), 156.5 bits, see alignment E=9.5e-50

Best Hits

KEGG orthology group: None (inferred from 59% identity to mrd:Mrad2831_5262)

Predicted SEED Role

"LysR family transcriptional regulator YeiE" in subsystem YeiH

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A168NAB6 at UniProt or InterPro

Protein Sequence (291 amino acids)

>A4249_RS02540 LysR family transcriptional regulator (Brevundimonas sp. GW460-12-10-14-LB2)
MTLERLRIFVAVAERDHVTAAARALNLTQSAVSNALAALEAEHDVRLFDRVGRGVVLNET
GRAFLPEAKAVLARAAAAEAALADMSALRRGRLAVFASQTIASYWLPRRLVDFHTAYPGV
ELAVEIGNTREAAQAVLSGAAEIGLVEGAVEESALSQVQVGSDRLAVLVTPDHPWATRRR
LDAKDLSDQPWVLREVGSGTRSTLEAAVRDIGVDPATLSVSMTLPSNEAVLAAAEAGAGA
TALSESVAYASVAAGRLVTAPFTLPERPFRLLRHRERYRSRAGDVFVEAMG