Protein Info for A4249_RS02525 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 271 PF04378: RsmJ" amino acids 33 to 269 (237 residues), 197.4 bits, see alignment E=1.2e-62

Best Hits

KEGG orthology group: K07115, (no description) (inferred from 70% identity to bsb:Bresu_2736)

Predicted SEED Role

"Protein involved in catabolism of external DNA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A168NA81 at UniProt or InterPro

Protein Sequence (271 amino acids)

>A4249_RS02525 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ (Brevundimonas sp. GW460-12-10-14-LB2)
MNYRHSFHAGNFADLVKHALVLWLVKVRQAAGPLAVFDTHAGAGLYDLSGDGARSKEAEA
GVARLMSAEGRTPLMDALAAEVAALNPEGGSRFYPGSPLLIADALTPGGRYVGFELNPPV
RAMLAEALAGRANAETREGDGYAAVVAEAAKTNGPLVLIDPPFEKPDDYVRSAETAIAVV
KRDPNTTVAIWTPLKDLETFDGFIRRLQGRAGSTLVAEARLRPLTNPMKMNGCAMVVVNP
PAGAEAAATQICGWVAGALGEAGGRAEVWTF