Protein Info for A4249_RS02450 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: short-chain fatty acyl-CoA regulator family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 474 PF13560: HTH_31" amino acids 7 to 65 (59 residues), 56.3 bits, see alignment E=9.9e-19 PF12844: HTH_19" amino acids 8 to 63 (56 residues), 40.4 bits, see alignment 7.4e-14 PF13413: HTH_25" amino acids 11 to 42 (32 residues), 27.5 bits, see alignment (E = 6.6e-10) PF01381: HTH_3" amino acids 11 to 63 (53 residues), 49.1 bits, see alignment 1.4e-16 PF06114: Peptidase_M78" amino acids 190 to 309 (120 residues), 78.8 bits, see alignment E=9.6e-26 PF09856: ScfRs" amino acids 310 to 464 (155 residues), 227.4 bits, see alignment E=2.4e-71

Best Hits

KEGG orthology group: K07110, (no description) (inferred from 63% identity to cak:Caul_2998)

Predicted SEED Role

"Transcriptional regulator, XRE family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A168N9T7 at UniProt or InterPro

Protein Sequence (474 amino acids)

>A4249_RS02450 short-chain fatty acyl-CoA regulator family protein (Brevundimonas sp. GW460-12-10-14-LB2)
MAEKLFLGAKLRKLREARGWTLEACAERLGLSPSYLSQIETNQRPATARVLIALTRAFHV
DASLFDLEGDARLIADLREATTDIAGQAEPPTAAELKQAVANTPRLAHQFLALHQTFRRL
DERVKALDDTLGRDEHGASVALLPYEEVRDFFHYRDNYIDTLDTAAEALATTLVQDGQIE
RALESALSQAHGVRVAYVAGQEALRRYDPASRVLTLDAWQPGATRSFQLAHQLALLSFRD
LIEAELDQAAFRTDAARDVARVGLANYAAGALLLPYRAFLEAAREEKHDIDRLRTRFQVS
FEQVCHRLSTLQRPGWRGVPFYFARVDMAGNITKRHSATRFQFARFGGACPLWNVHEAFA
APDRIGVQLAEMPDGSRYISIARSVSKPSGSYLANDRRYALSLGCEVEHAGALVYAAGLD
LNGPAARIGVSCRICERIDCTQRAFPPLDRTLHVPENERGVVPYVLDGPRPDRY