Protein Info for A4249_RS02290 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: holdfast anchoring protein HfaB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 338 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details PF03783: CsgG" amino acids 68 to 274 (207 residues), 44.7 bits, see alignment E=1e-15

Best Hits

Swiss-Prot: 65% identical to HFAB_CAUVC: Putative transcription activator protein HfaB (hfaB) from Caulobacter vibrioides (strain ATCC 19089 / CB15)

KEGG orthology group: K06214, curli production assembly/transport component CsgG (inferred from 81% identity to bsb:Bresu_2746)

Predicted SEED Role

"Curli production assembly/transport component CsgG" in subsystem Curli production

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A168N958 at UniProt or InterPro

Protein Sequence (338 amino acids)

>A4249_RS02290 holdfast anchoring protein HfaB (Brevundimonas sp. GW460-12-10-14-LB2)
MSRRHLIKGSAAVSAVALLLAGCVSPVAGPSGQYATPIGNAPVTANPTPYSAALYCLADY
ARRYNLPSPRMAVGRISDYTGTVSSDGGRQITGGASLMANSALAKAGARIVERYDTSVSE
LELRYANNKLIGDQAPDAKGPEDTQYRRILAGQVPGSDFYVVGGITEVNYNIRSGGFDIA
GGEVDSNRPGSGIVNHRVYVMNIAMDLRLVQTTTLEVVDVVSYQKQIIGREISAGVFDFL
NGNVFDISAGTGGMEPTQLAVRALVERATVEFMANLYGAPGPEICLNPANDPLGDSTVGP
TGGYYPAYPTQDTNNGQTRADPSRWHDGRDGDVRRTRH