Protein Info for A4249_RS02205 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: PhoH family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 263 PF02562: PhoH" amino acids 62 to 260 (199 residues), 271.5 bits, see alignment E=1.1e-84 PF13604: AAA_30" amino acids 66 to 219 (154 residues), 29.8 bits, see alignment E=1.2e-10 PF01695: IstB_IS21" amino acids 76 to 109 (34 residues), 24.5 bits, see alignment 4.6e-09 PF13245: AAA_19" amino acids 77 to 218 (142 residues), 29.9 bits, see alignment E=1.4e-10

Best Hits

KEGG orthology group: K06217, phosphate starvation-inducible protein PhoH and related proteins (inferred from 84% identity to bsb:Bresu_2752)

Predicted SEED Role

"Phosphate starvation-inducible protein PhoH, predicted ATPase" in subsystem Phosphate metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A168N8R7 at UniProt or InterPro

Protein Sequence (263 amino acids)

>A4249_RS02205 PhoH family protein (Brevundimonas sp. GW460-12-10-14-LB2)
MEASMTKRAATKRQTREHGILDSRDFMEESKVRRLHAPQNERSGWSPYPSNDDRDQGYLK
TLKPKSEGQGELMEAIDHHNLVMALGPAGTGKTYLAVAKAVEALEAGKVGRIVLSRPAVE
AGESIGFLPGDMEDKLAPYLRPLYDALSDRLSMKQIKALMAEGLIEIAPVGYMRGRTLNN
AFIVVDEAQNCTYVQLKMLLTRLGWHSTMVVTGDPQQSDLLPGISGLSDISARLEAVPDI
AVVRLAERDIVRHPLVASMIGVL