Protein Info for A4249_RS02035 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: glycoside hydrolase family 3 N-terminal domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 851 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details PF00933: Glyco_hydro_3" amino acids 86 to 408 (323 residues), 238.9 bits, see alignment E=1.5e-74 PF01915: Glyco_hydro_3_C" amino acids 445 to 656 (212 residues), 112.2 bits, see alignment E=5e-36 PF18559: Exop_C" amino acids 689 to 839 (151 residues), 120.8 bits, see alignment E=7.4e-39

Best Hits

KEGG orthology group: K01188, beta-glucosidase [EC: 3.2.1.21] (inferred from 75% identity to bsb:Bresu_2935)

Predicted SEED Role

"Periplasmic beta-glucosidase (EC 3.2.1.21)" in subsystem Beta-Glucoside Metabolism (EC 3.2.1.21)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.21

Use Curated BLAST to search for 3.2.1.21

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A161I7E6 at UniProt or InterPro

Protein Sequence (851 amino acids)

>A4249_RS02035 glycoside hydrolase family 3 N-terminal domain-containing protein (Brevundimonas sp. GW460-12-10-14-LB2)
MTLRILNSRQSAVSTLALGLVLMSSACAIDPGRVRAVPVQAVTAQASIVTDATRAHPALW
PRAASPAAMTDAATEAFVSELMSRMTLEEKVGQTIQADIGSIKPEDLLTYPLGSILAGGN
SSPGGDERASADKWVELARAFRAAAAQRPGARIPLIYGIDAVHGHNNIVGATIFPHNIGL
GAARDPDLIRRIGEATALEVAVTGADWTFGPTLAVPQDDRWGRAYEGYAENPEVAQSYAG
PMTLGLQGALSADHPLAAGHIAGSAKHFLADGGTTGGKDQGDFAGSEQELIRTHLSGYPQ
AIDAGVLSIMASFSSWNGVKHSGNETILTDVLRGPLGFDGFVVSDWNAHGQLPGCSNESC
ALAFNAGIDMFMAPDSWKPLYASTLAQVKSGEIPMARLDEAVRRILRVKVKTGLFNDSRP
VEGHLNELGSPAHRALAREAVRKSLVLLKNEGSVLPIHSGARVLVAGHADDIGQASGGWT
LTWQGTGNSNADFPNGQSIWGGIREAVAAGGGQATLSADGSFTQKPDVAIVVFGETPYAE
FQGDVDTLDFLPTEPLETLKRLKAAGIPTVSVFLSGRPMWTNPEINASDAFVAAWLPGTE
GGGIADVLVGDAAGKPRNDFTGTLSFSWPKTAKGEPLNVGQPGYDPQFAYGYGLTYARNT
RVGALSEDSGVVGAVGSLDRYFVDGRFVAPWSLMLRDAGGEFRLGSEKSGASPRGGVSVR
STDGAGQESARALTFSQGGGQALIAAQPVDLTRQSNGEMAIAFRYRVDARPKGPVFLTLG
AGSVDISSLIAAAPVGEWRTLKVRLSCLRDRGADIAAVDQPWGLRTAADFAVTVEDIRLA
SNEGDAVCPTQ