Protein Info for A4249_RS02010 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: DUF5597 domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02449: Glyco_hydro_42
  • amino acids 76 to 217 (142 residues), 38.2 bits, E=1.8e-13
• PF18120: DUF5597
  • amino acids 393 to 533 (141 residues), 116.5 bits, E=1.5e-37

Best Hits

KEGG orthology group: None (inferred from 57% identity to ccr:CC_0788)

Predicted SEED Role

"Beta-galactosidase (EC 3.2.1.23)" in subsystem Galactosylceramide and Sulfatide metabolism or Lactose and Galactose Uptake and Utilization or Lactose utilization (EC 3.2.1.23)

MetaCyc Pathways

• lactose degradation III (1/1 steps found)
• xyloglucan degradation II (exoglucanase) (5/8 steps found)

KEGG Metabolic Maps

• Galactose metabolism
• Glycosaminoglycan degradation
• Glycosphingolipid biosynthesis - ganglio series
• Other glycan degradation
• Sphingolipid metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.2.1.23

Sequence Analysis Tools

See A0A161IXH5 at UniProt or InterPro

Protein Sequence (548 amino acids)

>A4249_RS02010 DUF5597 domain-containing protein (Brevundimonas sp. GW460-12-10-14-LB2)
MGYFTRGFAAALSAATLVAAAASSVLAQSPIPQLVEQNGRHALMVDGAPFTILGGQVNNS
SNYPAPLAQAWPALRYIGANTVQIPLGWEQIEPEEGRFDFSFVDHAIEQARANDMRVVFL
WFATWKNTAPAYAPAWVKLNPERFPHLIEKSGKESYALSPYGVETLAADARAFAALMRHI
RQVDERKRTVIMVQPENEVGTYGPVRDYSPAARAAFDGPVPQALLDRTGKAPGTWSAVFG
KDADEFFHAWSIGHYVGQVAAAGKAEYPLPMYVNAALRDPTNDQDPATYASGGPTWNVIE
VWQAAAPSVDFLSPDIYTRKSGEYEAHLDRYARPDNALFVAETGSDTQYARYLMETLGRG
GIGFSPFGIDYTGYSNYPLGAKEITEKTLEPFRDLYRLIGPWQRTWARLAFEGKVWGAAE
PDDRKPEVIDLGDWTATTGYQRWQFGPSSQPIDPNDVPAASAQPNGAIAIAEIEPGQFIL
AGHRIRIDFAAKPSTDGKRRMVLRVEEGHFDDAGKWVFERIWNGDQVDYGLNFSTDRPQL
LRVVTATY