Protein Info for A4249_RS02005 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: TonB-dependent receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 964 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details TIGR01782: TonB-dependent receptor" amino acids 27 to 964 (938 residues), 635.3 bits, see alignment E=9.5e-195 PF07715: Plug" amino acids 47 to 156 (110 residues), 37.1 bits, see alignment E=3.9e-13 PF00593: TonB_dep_Rec" amino acids 388 to 925 (538 residues), 94.2 bits, see alignment E=1.7e-30

Best Hits

Predicted SEED Role

"N-acetylglucosamine-regulated TonB-dependent outer membrane receptor" in subsystem Chitin and N-acetylglucosamine utilization or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A160I0T3 at UniProt or InterPro

Protein Sequence (964 amino acids)

>A4249_RS02005 TonB-dependent receptor (Brevundimonas sp. GW460-12-10-14-LB2)
MLTVAATLPTAVLAQQAPAQSDDATTVDEVVVTGIRAQLRSAQAIKKNSEVIVDSVTAVD
IGALPDRSVSEALQRIPGVTLQRTNAARDPARLAAEGGGVFIRGLSWVRSETNGRDIFSA
SNGRGLSFEDVSADLLAGVDVYKNVAANMIEGGIAGTTNLRTRVPFDNSDPLLAINADYN
YGDLSEKGFWSGSILATDRWQTGIGEIGLLANVSVSNVGNRTDSISVDRYDPVTLNAGNA
STDGSGTAGETVFVPKYLGWRTIDWEQKRTAVALAAQWRPNDQWLFTLQGLASQADAYNV
EYALGTDSIVSPNSSYRYDDQNVFLSGNIPAATWNTDTRVGDDTKKTSDVALNFQYTPGG
AWSFSGDLQYVKSSAEIYSMTAFTQLQNRPDLSITIDGDLPTVTSTGGTPEDKSAYWWAA
AMDHIEDNEADELAGRLDARYDFDENSSFFKSVAFGVRGTEKNYTNRQTGYNWGLLSNQY
WGNGGGAVVYLDDTGYPGGTQDPRLPNSSTLYRFDNFFRGDAPVPGVAWFPAESLLNQGT
AYAYDILRNTESSGWGWTPLSDDYESYRLGGGNGGITELTEKTQAAYVYARFGNDTGFFG
RAFDGNIGLRAVDTKTTSNTVTTLPSIQGACPPANAPGANCAAFNQAVRFVNGGSLDGQP
VESSYTNWLPSLNLRGFLSDTLQARFAISRAMVRPEMYQLQPFTNLSINFQPDGYTLNPT
TPFTGVGGNPALRPITATNYDASLEWYFAPTGSLTFAAFHKDIKDYIFTGTETQSITNGG
VTYDFLITRYTNGAEGTVDGFELAYSQFFDFLPGAFSGLGFQGNFTYISSDGGKNTSQNI
LDTTQNGAASDSTLPLEGMSRTSYNAAILYEKYGISARLAYNWREEYLLTTSAANVNAPV
WASDYGQLDGSIFYNLTKDIKIGVQSTNILNERTILKVGSETRKPPYNWVDTDRRIAVVL
RAAF