Protein Info for A4249_RS01610 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: TetR/AcrR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 191 PF00440: TetR_N" amino acids 21 to 65 (45 residues), 52.1 bits, see alignment 4.6e-18 PF21597: TetR_C_43" amino acids 85 to 186 (102 residues), 43.6 bits, see alignment E=3e-15

Best Hits

KEGG orthology group: None (inferred from 53% identity to bsb:Bresu_0847)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A168N526 at UniProt or InterPro

Protein Sequence (191 amino acids)

>A4249_RS01610 TetR/AcrR family transcriptional regulator (Brevundimonas sp. GW460-12-10-14-LB2)
MTRHAEKPVRKDAALNRAAVLEAARAVFADQGLDAPLDLIAERAGVGRGTLYRHFSDRTE
LALAVLEADVADLGRRTAEQGDDPQAFFWFLDRLAEDMVRNAGLAGVVRNVRSPDALTPL
RQSLMEAGAAPLKRAQAAGLVREDLRPMDIRLIATLLGAGFQGADEAERQAVSLRTRALV
LDGLRPRGGAR