Protein Info for A4249_RS01520 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: putative peptidoglycan glycosyltransferase FtsW

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 391 transmembrane" amino acids 28 to 51 (24 residues), see Phobius details amino acids 63 to 84 (22 residues), see Phobius details amino acids 92 to 111 (20 residues), see Phobius details amino acids 130 to 147 (18 residues), see Phobius details amino acids 154 to 174 (21 residues), see Phobius details amino acids 180 to 197 (18 residues), see Phobius details amino acids 203 to 222 (20 residues), see Phobius details amino acids 276 to 300 (25 residues), see Phobius details amino acids 317 to 337 (21 residues), see Phobius details amino acids 349 to 370 (22 residues), see Phobius details PF01098: FTSW_RODA_SPOVE" amino acids 32 to 371 (340 residues), 248.9 bits, see alignment E=4e-78

Best Hits

Swiss-Prot: 62% identical to FTSW_CAUVN: Probable peptidoglycan glycosyltransferase FtsW (ftsW) from Caulobacter vibrioides (strain NA1000 / CB15N)

KEGG orthology group: K03588, cell division protein FtsW (inferred from 83% identity to bsb:Bresu_2777)

Predicted SEED Role

"Cell division protein FtsW" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A168N4I5 at UniProt or InterPro

Protein Sequence (391 amino acids)

>A4249_RS01520 putative peptidoglycan glycosyltransferase FtsW (Brevundimonas sp. GW460-12-10-14-LB2)
MSAPYTPAFSRNDQSHVAQWFWTVDRGLLGAALALMALGVALSFASSPAAILADESITDP
FHYSWRMMVFSGVGLSIMLTTSLMSPRGVRRIAVLALFGAIVVMMALPFIGDTVKGAARW
VNFGPFSLQPSEFAKPGLIVFAAWMFAEAQKGQGVPGVTIAFGFYALTVSLLLIQPDIGQ
TLLITTTFMAVFFMAGVPFKWMAVLASLGMAGLVSLYFVFGHMRDRLSRFFSPETTDTHQ
IDSASEAIRAGGLLGRGIGEGVMKRRVPDLHTDFIYSVGAEEFGLILSLIMISLYAFIVI
RGMRRAMKLTDPFEQTAAAGLFMLIGLQACINVAVNLNLIPTKGMTLPFISYGGSSMLAM
GLTMGFALALTRRRPGAYEPGASLTMGRRLL