Protein Info for A4249_RS01450 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: SIMPL domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 263 signal peptide" amino acids 1 to 40 (40 residues), see Phobius details PF04402: SIMPL" amino acids 58 to 259 (202 residues), 202 bits, see alignment E=6.6e-64

Best Hits

KEGG orthology group: K09807, hypothetical protein (inferred from 70% identity to bsb:Bresu_2755)

Predicted SEED Role

"Protein of unknown function DUF541"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A168N3Y8 at UniProt or InterPro

Protein Sequence (263 amino acids)

>A4249_RS01450 SIMPL domain-containing protein (Brevundimonas sp. GW460-12-10-14-LB2)
MTRTLAAAPLKTLSLKTVALGGAVAAAAFLAAATPRAMAQTAEPMGAVHMMQPAPSLNLS
AYGEVKAAPDMATITFGVQTEAVTAQQAMRDNAAQMTRVVAALRRAGIAERDIQTSGLNL
SAQYDYVQNEPPKLRGYQAVNRVTVVINDLSKVGTTADAVVAAGVNQIDGISFGLKDPTA
AENQARQLAVRNLQAKAQLYAQSLNVQLSGIRNLTEGGGYAPQPPMPMFAARAVSMDRAE
STPVSAGELTVRIDITGVYDIAR