Protein Info for A4249_RS00935 in Brevundimonas sp. GW460-12-10-14-LB2
Annotation: lytic transglycosylase domain-containing protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Predicted SEED Role
"Soluble lytic murein transglycosylase precursor (EC 3.2.1.-)" (EC 3.2.1.-)
KEGG Metabolic Maps
- Ascorbate and aldarate metabolism
- Glycosaminoglycan degradation
- Nucleotide sugars metabolism
- Ubiquinone and menaquinone biosynthesis
Isozymes
Compare fitness of predicted isozymes for: 3.2.1.-
Use Curated BLAST to search for 3.2.1.-
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A168N0L9 at UniProt or InterPro
Protein Sequence (561 amino acids)
>A4249_RS00935 lytic transglycosylase domain-containing protein (Brevundimonas sp. GW460-12-10-14-LB2) MFLFRRAILASTLVLAFCAATTAATAETPYGSTAEASAGSGRPTALSSADRISYTTAFDA LRRGDIETARMAARQAQDRVLLGQVEFESLFHPDHVATYEELTAWLETYSDLPCADRVYT LALRRRPDGAPEPVRPGGVLGRTWNSLVSAVSGDGGVTDPAKAARVAYNNDDLTGASALG RQIGDWWTVGLAEWRLGQFHESFAAFERVANDPTEDAWVRAGAAFWTARAAAQSGRQDRV TDYLRLSAQWPATFYGQIALRQLGEEPTIENMGPRPYEAEPRLRRAAYVPQSAAVEPTAL EAFVQADARAKRTVAFYEVGRNADAETELRSGLRTAVGDAAKMWTALARAILPVNNGDAT RIDATRYPMPDLAPEGGFVIERALVYALARKETDFNPNARSSVGAYGLMQVMPTTAAEMT GDRTFVSDPTKLLVPAVNMRLGQAYINKMLALPAFQGDLLRAVASYNAGPGPMLAAVRKL GADADPLLLIETIDVPQARDYVEKVMASYWIYQRLFGGPLKTLDAVASGARAVPMALDYV APPPQAEPVLIAETTPIAGAR