Protein Info for A4249_RS00935 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: lytic transglycosylase domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 561 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF01464: SLT" amino acids 380 to 479 (100 residues), 72.1 bits, see alignment E=1.5e-24

Best Hits

Predicted SEED Role

"Soluble lytic murein transglycosylase precursor (EC 3.2.1.-)" (EC 3.2.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.-

Use Curated BLAST to search for 3.2.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A168N0L9 at UniProt or InterPro

Protein Sequence (561 amino acids)

>A4249_RS00935 lytic transglycosylase domain-containing protein (Brevundimonas sp. GW460-12-10-14-LB2)
MFLFRRAILASTLVLAFCAATTAATAETPYGSTAEASAGSGRPTALSSADRISYTTAFDA
LRRGDIETARMAARQAQDRVLLGQVEFESLFHPDHVATYEELTAWLETYSDLPCADRVYT
LALRRRPDGAPEPVRPGGVLGRTWNSLVSAVSGDGGVTDPAKAARVAYNNDDLTGASALG
RQIGDWWTVGLAEWRLGQFHESFAAFERVANDPTEDAWVRAGAAFWTARAAAQSGRQDRV
TDYLRLSAQWPATFYGQIALRQLGEEPTIENMGPRPYEAEPRLRRAAYVPQSAAVEPTAL
EAFVQADARAKRTVAFYEVGRNADAETELRSGLRTAVGDAAKMWTALARAILPVNNGDAT
RIDATRYPMPDLAPEGGFVIERALVYALARKETDFNPNARSSVGAYGLMQVMPTTAAEMT
GDRTFVSDPTKLLVPAVNMRLGQAYINKMLALPAFQGDLLRAVASYNAGPGPMLAAVRKL
GADADPLLLIETIDVPQARDYVEKVMASYWIYQRLFGGPLKTLDAVASGARAVPMALDYV
APPPQAEPVLIAETTPIAGAR