Protein Info for A4249_RS00760 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: carbon starvation CstA family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 695 transmembrane" amino acids 7 to 27 (21 residues), see Phobius details amino acids 33 to 52 (20 residues), see Phobius details amino acids 91 to 111 (21 residues), see Phobius details amino acids 117 to 138 (22 residues), see Phobius details amino acids 159 to 183 (25 residues), see Phobius details amino acids 191 to 209 (19 residues), see Phobius details amino acids 221 to 241 (21 residues), see Phobius details amino acids 255 to 276 (22 residues), see Phobius details amino acids 284 to 303 (20 residues), see Phobius details amino acids 321 to 344 (24 residues), see Phobius details amino acids 365 to 385 (21 residues), see Phobius details amino acids 397 to 416 (20 residues), see Phobius details amino acids 436 to 457 (22 residues), see Phobius details amino acids 465 to 485 (21 residues), see Phobius details amino acids 510 to 529 (20 residues), see Phobius details amino acids 542 to 566 (25 residues), see Phobius details amino acids 573 to 593 (21 residues), see Phobius details amino acids 642 to 662 (21 residues), see Phobius details PF02554: CstA" amino acids 32 to 408 (377 residues), 581.4 bits, see alignment E=7.3e-179 PF13722: CstA_5TM" amino acids 463 to 591 (129 residues), 138.6 bits, see alignment E=1.3e-44

Best Hits

Swiss-Prot: 67% identical to CSTA_ECOLI: Peptide transporter CstA (cstA) from Escherichia coli (strain K12)

KEGG orthology group: K06200, carbon starvation protein (inferred from 69% identity to cti:RALTA_A3164)

MetaCyc: 67% identical to pyruvate transporter CstA (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-335

Predicted SEED Role

"Carbon starvation protein A"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A168MZT1 at UniProt or InterPro

Protein Sequence (695 amino acids)

>A4249_RS00760 carbon starvation CstA family protein (Brevundimonas sp. GW460-12-10-14-LB2)
MGKLSTPIIFGAIAILGAVSLGIIALHQGESISAVWMVVAAVCTYAIAYRFYSRYLANKV
MQLNPARLTPAMRRNDGLDYVPTPKNVLFGHHFAAIAGAGPLVGPVLAAQMGYLPGVLWI
LVGAVLAGAVQDMMVLFMSTRRDGKSLGDMIRTEMGNIPGIIAQVGVLMIMVIILAVLAL
VVVKALAESPWGTFTVAATIPIAIFMGLYTRFLRPGRVGEVSVIGVVLLMLAIIGGGHIA
ADPFWGPAFTLTGPTLAILMMVYGFIASVIPVWLLLAPRDYLSTFLKIGAIVALAVGILI
VRPHLQMPAITPFIDGTGPVFAGALFPFLFITIACGAVSGFHALISSGTTPKLLENEAQI
PMIGYGAMLCESFVAVMALIAATVLDPAVYFAMNSPVAVIGNDAVSAAAAVAQWGFHITP
GELEQLARDVGEHSILSRAGGAPTLAVGMAHILSGVIGGKAMMAFWYHFAILFEALFILT
TVDAGTRVCRFMIQDLLGVAVPKMRETKSWGANVVATALTVGLWGYFLYTGVVDPLGGIN
SLWPLFGIANQMLAAVALILGTVVLFKMKREKFAWVMVVPATWLLICTLTAGFQKLFHPD
VRIGFLSHARKYQEALGAGELIAPAKSIGDMHRIVVNDYVNSTLTAGFLFVVVTMVVYGV
LACRKAYANNRPTVREYPESHQLTAADEAADAARA