Protein Info for A4249_RS00425 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: VOC family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 127 PF00903: Glyoxalase" amino acids 3 to 121 (119 residues), 27.2 bits, see alignment E=4.6e-10 PF18029: Glyoxalase_6" amino acids 5 to 122 (118 residues), 28 bits, see alignment E=3e-10

Best Hits

KEGG orthology group: None (inferred from 85% identity to bsb:Bresu_3127)

Predicted SEED Role

"Lactoylglutathione lyase and related lyases"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A168MXN7 at UniProt or InterPro

Protein Sequence (127 amino acids)

>A4249_RS00425 VOC family protein (Brevundimonas sp. GW460-12-10-14-LB2)
MFTHVTVGANDIEASRRFYDAALGALGVEPGQGPDPKGRYWWRTRMGAFAIGAPIDGEPA
CHANGGTIGFHAKTAEMVQAFHDAGVAAGGRAIEDPPGERKGPFGPMILAYLRDPSGNKI
CAMHRVG