Protein Info for A4249_RS00275 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 623 transmembrane" amino acids 25 to 43 (19 residues), see Phobius details amino acids 49 to 69 (21 residues), see Phobius details amino acids 81 to 101 (21 residues), see Phobius details amino acids 107 to 126 (20 residues), see Phobius details amino acids 133 to 156 (24 residues), see Phobius details amino acids 162 to 179 (18 residues), see Phobius details PF00512: HisKA" amino acids 213 to 274 (62 residues), 37.7 bits, see alignment E=2.6e-13 PF02518: HATPase_c" amino acids 321 to 434 (114 residues), 98.9 bits, see alignment E=3.7e-32 PF00072: Response_reg" amino acids 496 to 607 (112 residues), 88.2 bits, see alignment E=6.2e-29

Best Hits

Predicted SEED Role

"sensor histidine kinase/response regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A168MWT6 at UniProt or InterPro

Protein Sequence (623 amino acids)

>A4249_RS00275 ATP-binding protein (Brevundimonas sp. GW460-12-10-14-LB2)
MKSTAVDIAESSWTAAVRQRSGAAVQRLVAAAAVALVVTPMVGVRFTFGWVVLYMAVQAM
EVVVYRPILKSPDELSTGRKLAILAVVFANSTVFSSLSLVLWWIGGAFGGVCAVLMLTAV
MLTAIVNATRCQAVMIAGLTPQVGFLLATPFFVYALHAPGPLVMSAAAAVVLFTFYVAIT
GQRMVEASVTVIRAHALAEESRLKAERSLADHTTFLAAIGHDLRTPIGAILAGAAELRTP
DAQSRNSANLITDAGLMMKALLDDLLDHTRIGAGRMTVEAKDFDLRQMLAQTLMLWRGVA
DAKGLKLRIEGASAMPRHVKGDVMRIRQVLNNLMSNAMKFTEQGQITLRVQAWPEEPSGY
ALLFEIVDTGPGMTTDQLARLFTPFDQTADGVSARYGGSGLGLAISRNLIDLMGGRLTVR
SATGQGSRFTVSLILPRGDEAVQIVEVVDQSRLDIARSLTPAVVAPAPVAPEPEPEPVAS
TPAVADEVEDQPLRLLVVDDHDINRRAVQLILQPLGCEITTAADGMIALERCQEAVFDVI
FMDVRMPELDGRETTRRLRAGGGPNAATPVVAVTADTAPEDVAACQAAGMAYFVSKPLTP
PALIGALQHVLNDTAAQAATEAA