Protein Info for A4249_RS00150 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: pitrilysin family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 404 PF00675: Peptidase_M16" amino acids 6 to 141 (136 residues), 108.7 bits, see alignment E=2.5e-35 PF05193: Peptidase_M16_C" amino acids 154 to 319 (166 residues), 122.5 bits, see alignment E=2e-39

Best Hits

KEGG orthology group: None (inferred from 79% identity to bsb:Bresu_0809)

Predicted SEED Role

"Mitochondrial processing peptidase-like protein (EC 3.4.24.64)" in subsystem ZZ gjo need homes (EC 3.4.24.64)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.24.64

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A160I0Q4 at UniProt or InterPro

Protein Sequence (404 amino acids)

>A4249_RS00150 pitrilysin family protein (Brevundimonas sp. GW460-12-10-14-LB2)
MPGLKTLAVVVTVKGGARWEPLDRSGWSHLLEHLVFKGAGDMAAREIVERIEAEGGTINA
STGYERTSFEVRGLDGSLPLAMQVLSDLVFRPTLDPAEIEREKDVVAQEIAEAFDTPDDH
VFEMVQTRAFAKQPLGRPILGSVASLKPADKALVEAWRARLYSPDRMVVSVSGAVEETEL
LALAERWFGDAVATPADAPAPAAFVGGHAKLTRKIEQANLVFQLPALSATDPALSAMRLF
GEILGGGMASRLFQSAREERGLAYAIDAYQEPYEDTGVLGIYAGAAADRAKELAEVSAAE
VRALAENGPTEKELSRAKAVMKAGLWMSDENPMSRAGRNAAQTLIFGAPRSSLSMTEQLE
GQTIEAVRAVGGRLLASGQAASAVLGPKSAAPAGEAFAAALFGG