Protein Info for A4249_RS00085 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: UbiA family prenyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 343 transmembrane" amino acids 35 to 54 (20 residues), see Phobius details amino acids 64 to 88 (25 residues), see Phobius details amino acids 109 to 130 (22 residues), see Phobius details amino acids 135 to 153 (19 residues), see Phobius details amino acids 165 to 189 (25 residues), see Phobius details amino acids 216 to 240 (25 residues), see Phobius details amino acids 263 to 282 (20 residues), see Phobius details amino acids 288 to 305 (18 residues), see Phobius details amino acids 325 to 342 (18 residues), see Phobius details PF01040: UbiA" amino acids 57 to 322 (266 residues), 173.5 bits, see alignment E=2.5e-55

Best Hits

Predicted SEED Role

"4-hydroxybenzoate polyprenyltransferase (EC 2.5.1.39)" (EC 2.5.1.39)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.5.1.39

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A168MVW6 at UniProt or InterPro

Protein Sequence (343 amino acids)

>A4249_RS00085 UbiA family prenyltransferase (Brevundimonas sp. GW460-12-10-14-LB2)
MTFAPLPDAGANWVDRHAPEGLKPWLKLGRFDRPIGIWLLLLPGWQGIALALAQYRQAPG
LYDLWLFVGFGIGACLMRAAGCAFNDIVDRDFDARVARTAQRPIPSGRISVKQAWAFVVA
CSLISLLVLLTLPTVAVGLGVGSLALVAAYPFMKRITWWPQAWLGLTFNWGALMGFAAAL
PLAAAALLLPADLAGEFRPFLWSPASESGHAIALTWQAYLPAVLLWIGGVFWTLGYDTIY
ALQDIEDDAMIGVKSSARRLASAVRPGVAVFYGLAVALAVLTGLSANLGPLFWLGLLIYA
AHLARQVVRLDRNDGALALKLFKSNREAGLILLAAIALGSISL