Protein Info for A4249_RS00055 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 216 PF10294: Methyltransf_16" amino acids 58 to 176 (119 residues), 32.2 bits, see alignment E=1.8e-11 PF05175: MTS" amino acids 64 to 144 (81 residues), 29.3 bits, see alignment E=1.3e-10 PF06325: PrmA" amino acids 77 to 146 (70 residues), 36.8 bits, see alignment E=6.4e-13

Best Hits

KEGG orthology group: None (inferred from 74% identity to bsb:Bresu_0903)

Predicted SEED Role

"SAM-dependent methyltransferases"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A168MVN5 at UniProt or InterPro

Protein Sequence (216 amino acids)

>A4249_RS00055 methyltransferase (Brevundimonas sp. GW460-12-10-14-LB2)
MTVLDPAAFIRDNTRLQPVPHAPEISLWLADEITPIWRLTEEELGEMGVPPPFWAFAWAG
GQALSRYLLDHPHEVVGKRVLDFAAGSGLVGVAAMQAGATHVLCADIDPFCQAAVAANAT
ANGVTLDFTQTNLLDAAPPDVDVICAGDICYERPMTDAVLAWLAQARAKGTRVLIGDPGR
TYFPRTGLDFLAEYRVPTSRELEDQEIKRSSVWAMP