Protein Info for b3578 in Escherichia coli BW25113

Name: yiaN
Annotation: predicted transporter (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 425 transmembrane" amino acids 12 to 35 (24 residues), see Phobius details amino acids 53 to 73 (21 residues), see Phobius details amino acids 93 to 124 (32 residues), see Phobius details amino acids 136 to 159 (24 residues), see Phobius details amino acids 170 to 191 (22 residues), see Phobius details amino acids 210 to 231 (22 residues), see Phobius details amino acids 240 to 259 (20 residues), see Phobius details amino acids 263 to 265 (3 residues), see Phobius details amino acids 276 to 295 (20 residues), see Phobius details amino acids 314 to 343 (30 residues), see Phobius details amino acids 355 to 376 (22 residues), see Phobius details amino acids 396 to 420 (25 residues), see Phobius details PF06808: DctM" amino acids 7 to 415 (409 residues), 462.2 bits, see alignment E=7.6e-143 TIGR00786: TRAP transporter, DctM subunit" amino acids 17 to 418 (402 residues), 523.2 bits, see alignment E=2e-161

Best Hits

Swiss-Prot: 100% identical to YIAN_ECOLI: 2,3-diketo-L-gulonate TRAP transporter large permease protein YiaN (yiaN) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to eco:b3578)

MetaCyc: 100% identical to 2,3-diketo-L-gulonate:Na+ symporter - membrane subunit (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-235

Predicted SEED Role

"2,3-diketo-L-gulonate TRAP transporter large permease protein yiaN"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P37675 at UniProt or InterPro

Protein Sequence (425 amino acids)

>b3578 predicted transporter (NCBI) (Escherichia coli BW25113)
MAVLIFLGCLLGGIAIGLPIAWALLLCGAALMFWLDMFDVQIMAQTLVNGADSFSLLAIP
FFVLAGEIMNAGGLSKRIVDLPMKLVGHKPGGLGYVGVLAAMIMASLSGSAVADTAAVAA
LLVPMMRSANYPVNRAAGLIASGGIIAPIIPPSIPFIIFGVSSGLSISKLFMAGIAPGMM
MGATLMLTWWWQASRLNLPRQQKATMQEIWHSFVSGIWALFLPVIIIGGFRSGLFTPTEA
GAVAAFYALFVATVIYREMTFATLWHVLIGAAKTTSVVMFLVASAQVSAWLITIAELPMM
VSDLLQPLVDSPRLLFIVIMVAILIVGMVMDLTPTVLILTPVLMPLVKEAGIDPIYFGVM
FIINCSIGLITPPIGNVLNVISGVAKLKFDDAVRGVFPYVLVLYSLLVVFVFIPDLIILP
LKWIN