Protein Info for b3530 in Escherichia coli BW25113

Name: bcsC
Annotation: cellulose synthase subunit (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1157 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF13432: TPR_16" amino acids 274 to 336 (63 residues), 28.8 bits, see alignment 7.8e-10 amino acids 356 to 418 (63 residues), 34.7 bits, see alignment 1.2e-11 amino acids 389 to 450 (62 residues), 24.1 bits, see alignment 2.3e-08 PF07719: TPR_2" amino acids 304 to 335 (32 residues), 23 bits, see alignment (E = 3.3e-08) PF13181: TPR_8" amino acids 304 to 334 (31 residues), 25.3 bits, see alignment (E = 6.2e-09) PF13176: TPR_7" amino acids 305 to 334 (30 residues), 18.2 bits, see alignment (E = 1.1e-06) PF14559: TPR_19" amino acids 615 to 682 (68 residues), 32.4 bits, see alignment 5.3e-11 PF05420: BCSC_C" amino acids 802 to 1136 (335 residues), 403.3 bits, see alignment E=5.1e-124

Best Hits

Swiss-Prot: 100% identical to BCSC_ECOLI: Cellulose synthase operon protein C (bcsC) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to ecl:EcolC_0187)

Predicted SEED Role

"Cellulose synthase operon protein C"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P37650 at UniProt or InterPro

Protein Sequence (1157 amino acids)

>b3530 cellulose synthase subunit (RefSeq) (Escherichia coli BW25113)
MRKFTLNIFTLSLGLAVMPMVEAAPTAQQQLLEQVRLGEATHREDLVQQSLYRLELIDPN
NPDVVAARFRSLLRQGDIDGAQKQLDRLSQLAPSSNAYKSSRTTMLLSTPDGRQALQQAR
LQATTGHAEEAVASYNKLFNGAPPEGDIAVEYWSTVAKIPARRGEAINQLKRINADAPGN
TGLQNNLALLLFSSDRRDEGFAVLEQMAKSNAGREGASKIWYGQIKDMPVSDASVSALKK
YLSIFSDGDSVAAAQSQLAEQQKQLADPAFRARAQGLAAVDSGMAGKAIPELQQAVRANP
KDSEALGALGQAYSQKGDRANAVANLEKALALDPHSSNNDKWNSLLKVNRYWLAIQQGDA
ALKANNPDRAERLFQQARNVDNTDSYAVLGLGDVAMARKDYPAAERYYQQTLRMDSGNTN
AVRGLANIYRQQSPEKAEAFIASLSASQRRSIDDIERSLQNDRLAQQAEALENQGKWAQA
AALQRQRLALDPGSVWITYRLSQDLWQAGQRSQADTLMRNLAQQKSNDPEQVYAYGLYLS
GHDQDRAALAHINSLPRAQWNSNIQELVNRLQSDQVLETANRLRESGKEAEAEAMLRQQP
PSTRIDLTLADWAQQRRDYTAARAAYQNVLTREPANADAILGLTEVDIAAGDKAAARSQL
AKLPATDNASLNTQRRVALAQAQLGDTAAAQRTFNKLIPQAKSQPPSMESAMVLRDGAKF
EAQAGDPTQALETYKDAMVASGVTTTRPQDNDTFTRLTRNDEKDDWLKRGVRSDAADLYR
QQDLNVTLEHDYWGSSGTGGYSDLKAHTTMLQVDAPYSDGRMFFRSDFVNMNVGSFSTNA
DGKWDDNWGTCTLQDCSGNRSQSDSGASVAVGWRNDVWSWDIGTTPMGFNVVDVVGGISY
SDDIGPLGYTVNAHRRPISSSLLAFGGQKDSPSNTGKKWGGVRADGVGLSLSYDKGEANG
VWASLSGDQLTGKNVEDNWRVRWMTGYYYKVINQNNRRVTIGLNNMIWHYDKDLSGYSLG
QGGYYSPQEYLSFAIPVMWRERTENWSWELGASGSWSHSRTKTMPRYPLMNLIPTDWQEE
AARQSNDGGSSQGFGYTARALLERRVTSNWFVGTAIDIQQAKDYAPSHFLLYVRYSAAGW
QGDMDLPPQPLIPYADW